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Keratins and lipids in ethnic hair
Cruz, Célia F.; Fernandes, Margarida M.; Gomes, Andreia; Coderch, L.; Martí, M.; Méndez, Sandra; Gales, Luís; Azoia, Nuno G.; Shimanovich, UlyanaHuman hair has an important and undeniable relevance in society due to its important role in visual appearance and social communication. Hair is mainly composed of structural proteins, mainly keratin and keratin associated proteins, and lipids. Herein, we report a comprehensive study of the content and distribution of the lipids among ethnic hair, African, Asian and Caucasian hair. More interestingly, we also r...
Production and characterization of extracellular carbohydrate polymer from Cyan...
Mota, Rita; Guimarães, Rodrigo; Büttel, Zsófia; Rossi, Federico; Colica, Giovanni; Silva, Carla J.; Santos, Carla; Gales, Luís; Zille, AndreaCyanobacterial extracellular polymeric substances (EPS) are heteropolysaccharides that possess characteristics suitable for industrial applications, notably a high number of different monomers, strong anionic nature and high hydrophobicity. However, systematic studies that unveil the conditions influencing EPS synthesis and/or its characteristics are mandatory. In this work, Cyanothece sp. CCY 0110 was used as ...
Towards a structural understanding of the fibrillization pathway in Machado-Jos...
Gales, Luís; Cortes, Luísa; Almeida, Carla; Melo, Carlos V.; Costa, Maria do Carmo; Maciel, P.; Clarke, David T.; Damas, Ana MargaridaMachado-Joseph’s disease is caused by a CAG trinucleotide repeat expansion that is translated into an abnormally long polyglutamine tract in the protein ataxin-3. Except for the polyglutamine region, proteins associated with polyglutamine diseases are unrelated, and for all of these diseases aggregates containing these proteins are the major components of the nuclear proteinaceous deposits found in the brain. A...
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