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In vitro testing strategy for nanomaterials including database (Deliverable 5):...
Norppa, Hannu; Siivola, Kirsi; Fessard, Valérie; Tarantini, Adeline; Apostolova, Margarita; Jacobsen, Nicklas Raun; Wallin, Håkan; Goetz, Mario E.WP5 had two objectives: - To generate in vitro genotoxicity data on manufactured MNs (specific objective #3). - To perform a round robin test on in vitro genotoxicity testing of MNs (specific objective #4) WP5 addressed the basic questions of in vitro genotoxicity testing of manufactured nanomaterials (MNs): how well in vitro assays can be used for revealing the genotoxic potential of MNs, which assays are suit...
Genotoxicity evaluation of three classes of manufactured nanomaterials on prima...
Tavares, Ana; Louro, Henriqueta; Antunes, Susana; Quarré, Stéphanie; Simar, Sophie; Nesslany, Fabrice; Silva, Maria JoãoHuman exposure to manufactured nanomaterials (MNMs) through consumers’ goods has increased worldwide, including titanium dioxide (TiO2), multiwalled carbon-nanotubes (MWCNT) and silicon dioxides (SiO2). Specific properties of MNMs, such as size and high surface area/mass, render them attractive for many applications, but may also be associated to higher toxicity in biological systems and adverse effects in huma...
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