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Exploitation of a link between antibacterial agent-resistance and biofilm-forma...
João, Inês; Reis, Lúcia; Carvalho, Patrícia; Duarte, Aida; Jordão, LuisaObjectives: In recent years nosocomial infections have gained growing importance. Among their etiological agents are “classical” pathogens such as S.aureus and also emergent pathogens, previously neglected, such as nontuberculous mycobacteria (MTM). The ability to resist to antibacterial agents, such as antibiotics and disinfectants, is shared by all of them. Here we aim to establish a link between bacterial vi...
Exploring a link between pathogens structure's and resistance to
João, Inês; Reis, Lúcia; Carvalho, Patrícia; Duarte, Aida; Jordão, LuisaIn recent years healthcare-associated infections (HAIs) infections have gained growing importance. Among their etiological agents are classical (e.g. K. pneumoniae, S. aureus) and emergent pathogens, previously neglected, such as nontuberculous mycobacteria (NTM). The ability to resist to antibacterial agents, such as antibiotics and disinfectants, is shared by all of them. Here we aim to establish a link betwe...
Bacterial biofilms, antibiotic resistance and healthcare-associated infections:...
Bandeira, Maria; Carvalho, Patrícia; Duarte, Aida; Jordão, LuisaIn 2012, were estimated 6.7 million cases of healthcare-associated infections (HAI) either in long-term care facilities or acute-care hospitals from which result 37,000 deaths configuring a serious public health problem [1]. The etiological agents are diverse and often resistant to antimicrobial agents. One of the mechanisms responsible for the emergence of drug resistance is biofilm assembly. Biofilms are defi...
Exploring a link between mycobacteria structure and virulence
Silva, Carla; Perdigao, Joao; Alverca, Elsa; Matos, António Pedro Alves; Carvalho, Patrícia A; Portugal, Isabel; Jordao, LuisaTuberculosis (TB) is a major health problem. The emergence of multidrug resistant (MDR)Mycobacterium tuberculosis (Mtb) isolates confounds treatment strategies. In Portugal, cases of MDR-TB are reported annually with increased incidence noted in Lisbon. The majority of these MDR-TB cases are due to closely-related mycobacteria known collectively as Lisboa family and Q1 cluster. The genetic determinants linked t...
Notice on a methodology for characterizing emissions of ultrafine particles/nan...
Gomes, João Pereira; Albuquerque, Paula Cristina; Esteves, Helder Manuel; Carvalho, Patrícia AlmeidaBearing in mind the potential adverse health effects of ultrafine particles, it is of paramount importance to perform effective monitoring of nanosized particles in several microenvironments, which may include ambient air, indoor air, and also occupational environments. In fact, effective and accurate monitoring is the first step to obtaining a set of data that could be used further on to perform subsequent eva...
Predictors of attrition and immunological failure in HIV- 1 patients on highly ...
Palladino, Claudia; Briz, Verónica; Bellón, José María; Bártolo, Inês; Carvalho, Patrícia; Camacho, Ricardo; Munõz-Fernandes, M. Ángeles; Bastos, Rui"In Mozambique, the evaluation of retention in HIV care and ART programmes is limited. To assess rate and predictors of attrition (no retention in care) and HAART effectiveness in HIV-1 infected patients who pay for medication and laboratory testing in Mozambique, we conducted a multicenter survey of HIV-1-infected patients who started HAART during 2002– 2006. Cox proportional hazard models were used to assess ...
Hábitos de estudo e sua influência no rendimento escolar
Carvalho, Patrícia da SilvaDissertação apresentada à Universidade Fernando Pessoa como parte dos requisitos para a obtenção do grau de Mestre em Psicologia, especialização em Psicologia Clínica e da Saúde ; O principal objetivo desta dissertação foi analisar os hábitos de estudo tanto em relação aos resultados escolares como em relação ao número de retenções dos alunos, dando-se especial atenção a duas facetas/índices dos hábitos de est...
Morphologic characterization of Mycobacterium tuberculosis circulating strains ...
Silva, Carla; Alverca, Elsa; Matos, António Pedro; Carvalho, Patricia A; Portugal, Isabel; Jordao, LuisaAbstrat publicado em: http://metallica.civil.ist.utl.pt/~patricia/SPMicros2012/book.pdf ; Tuberculosis (TB) is one of the major causes of mortality and morbidity worldwide accounting for 3.1 million deaths per year. This disease, caused by M. tuberculosis (Mtb) made a deadly, during the 1990’s, triggered mainly by the emergence of acquired immunodeficiency syndrome (AIDS). More recently, the emergence of multi...
Medição do teor de humidade em materiais de construção
Carvalho, PatríciaTese de mestrado integrado. Engenharia Civil. Faculdade de Engenharia. Universidade do Porto. 2010
Digital ulcers in systemic sclerosis: use of endotheline antagonists.
Mota, Joana; Castellano, Amparo; Santiago, Felicidade; Carvalho, Patrícia; Madeira, A Sofia; Pereira De Moura, J M; Nascimento Costa, J MSystemic sclerosis (SSc) is a systemic disease, characterized by fibrosis and vasculopathy, with variable internal organ involvement. Skin is very often involved, namely digital ulcers (DU), seldom treatment resistant, responsible for important functional limitation. The DU can evolve from sclerodactily with superficial ulcers, isquemic lesions, deep necrosis, gangrene, loss of tissue, and consequently, to fing...
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