Encontrados 2 documentos, a visualizar página 1 de 1
Sources of glucose production in cirrhosis by 2H2O ingestion and 2H NMR analysi...
Perdigoto, Rui; Furtado, Alexandre L.; Porto, Armando; Rodrigues, Tiago B.; Geraldes, Carlos F. G. C.; Jones, John G.Plasma glucose 2H enrichment was quantified by 2H NMR in patients with cirrhosis (n=6) and healthy subjects (n=5) fasted for 16 h and given 2H2O to ~0.5% body water. The percent contribution of glycogenolysis and gluconeogenesis to glucose production (GP) was estimated from the relative enrichments of hydrogen 5 and hydrogen 2 of plasma glucose. Fasting plasma glucose levels were normal in both groups (87±7 an...
Integration of [U-13C]glucose and 2H2O for quantification of hepatic glucose pr...
Perdigoto, Rui; Rodrigues, Tiago B.; Furtado, Alexandre L.; Porto, Armando; Geraldes, Carlos F. G. C.; Jones, John G.Glucose metabolism in five healthy subjects fasted for 16 h was measured with a combination of [U-13C]glucose and 2H2O tracers. Phenylbutyric acid was also provided to sample hepatic glutamine for the presence of 13C-isotopomers derived from the incorporation of [U-13C]glucose products into the hepatic Krebs cycle. Glucose production (GP) was quantified by 13C NMR analysis of the monoacetone derivative of plasm...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||