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Bone mechanical stimulation with piezoelectric materials
Reis, J; Frias, C; Capela e Silva, F; Potes, J; Simões, JA; Botelho, MI; Castro, CC; Marques, ATThis chapter summarized explores in vivo use of a piezoelectric polymer for bone mechanical stimulation
A new piezoelectric actuator induces bone formation in vivo: a preliminary study
Reis, J; Frias, C; Canto e Castro, C; Botelho, ML; Marques, AT; Simões JA, JA; Capela e Silva, F; Potes, JThis in vivo study presents the preliminary results of the use of a novel piezoelectric actuator for orthopedic application. The innovative use of the converse piezoelectric effect to mechanically stimulate bone was achieved with polyvinylidene fluoride actuators implanted in osteotomy cuts in sheep femur and tibia. The biological response around the osteotomies was assessed through histology and histomorphomet...
Piezoelectric actuators for bone mechanical stimulation: exploring the concept.
Reis, J; Frias, C; Capela e Silva, F; Potes, J; Botelho, ML; Canto e Castro, C; Marques, AT; Simões, JAArthroplasty is liable to cause intense changes on strain levels and distribution in the boné surrounding the implant, namely stress shielding. Several solutions have been proposed for this, namely design variations and development of controlled-stiffness implants. A new approach to this problem, with potential application to other orthopaedic problems and other medical fields, would be the development of smart...
Piezoelectric actuator: searching inspiration in nature for osteoblast stimulation
Frias, C; Reis, J; Capela e Silva, F; Potes, J; Simões, J; Marques, ATBone is a composite with piezoelectric properties. Bone mass and structure are dependent on mechanical stress and adaptive response at cellular and tissue levels, but the role piezoelectricity plays in bone physiology is yet to be understood. Physical activity enhances bone density, through mechanical stimulation. Osteocytes and osteoblasts are essential for mechanosensing and mechanotransduction. Strategies ha...
Polymeric piezoelectric actuator substrate for osteoblast mechanical stimulation.
Frias, C; Reis, J; Capela e Silva, F; Potes, J; Simões, J; Marques, ATBone mass distribution and structure are dependent on mechanical stress and adaptive response at cellular and tissue levels. Mechanical stimulation of bone induces new bone formation in vivo and increases the metabolic activity and gene expression of osteoblasts in culture. A wide variety of devices have been tested for mechanical stimulation of cells and tissues in vitro. The aim of this work was to experiment...
Behaviour of piozoelectric devices embedded in bone cement
Frias, C.; Marques, M.A.; Ribeiro, J.E.; Vaz, M.A.P.; Simões, J.; Marques, A.T.Bone cements based on polymethacrylate (PMMA) are essential products in joint arthroplasty. PMMA bone cement function is to locate the implants components in the body skeleton, load transition through the joint into the bone and muscle surrounding for a very for a very long period of time. Its mechanical properties are well established in the literature. Since bone cement fills the void between the prosthesis (...
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