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Recurrent hypercortisolism after removal of an ACTH secretor pituitary adenoma ...
Santos, Jacinta; Paiva, Isabel; Gomes, Leonor; Batista, Carla; Geraldes, Elisabete; Rito, Manuel; Velez, Ana; Oliveira, Fernando; Carvalheiro, ManuelaA 29 years old patient was sent to our Outpatient Clinic of Endocrinology presenting clinic of hypercortisolism. Laboratorial study: High urinary free cortisol (UFC); serum cortisol - 25 microg/dl (8 am) (5-25) and 20 microg/dL (11pm); ACTH - 20 pg/mL (9-52) (8 am) and 14 pg/mL (11 pm); serum cortisol after dexamethasone suppression test: 14,9 mg/dL; CRH test: elevation of ACTH; Pituitary MRI: microadenoma; abd...
ACTH-dependent Cushing's syndrome: a revision of 43 cases.
Paiva, Isabel; Ribeiro, Cristina; Gomes, Leonor; Baptista, Carla; Gomes, Fernando; Rito, Manuel; Rebelo, Olinda; Marnoto, Dina; Moura, CristinaTo evaluate the characteristics and outcomes of the patients diagnosed as ACTH-dependent Cushing syndrome, registered in the department.We reviewed the files of forty-three patients followed from 1974 to 2002.A progressive rise in the number of patients diagnosed was found, being 80% females. Clinical suspicion was based mostly on the typical fat distribution; hirsutism and amenorrhoea were important in women. ...
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