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Skin aging. Physiopathology and clinical perspective.

The main structural and functional alterations observed during skin ageing are reviewed, considering the intrinsic process of senescence and the damage induced by chronic exposure to actinic radiation. In photo-ageing the importance of skin type is stressed, concerning its capacity to tan in order to get protection against radiation. Finally some inflammatory, degenerative and neoplastic skin diseases associate...

Peripheral tissue oxygenation in patients with congestive heart failure.

Foi estudada a função respiratória do sangue em 21 doentes de ambos os sexos com insuficiência cardíaca, predominantemente do ventrículo esquerdo, em fase de descompensação. A par de ligeira, mas significativa, diminuição da concentração de hemoglobina verificou-se acentuado aumento do 2,3--difosfoglicerato (2,3-DPG) eritrocitário, associado a maior capacidade de cedência de oxigénio aos tecidos, alcalemia e hi...

Erythrocyte metabolism in human hypothyroidism, before and after short-term hor...

Analisou-se a influência exercida pelo tratamento hormonal substitutivo no metabolismo eritrocitário de 16 doentes com hipotiroidismo primário, estudados antes e durante terapêutica com tiroxina. Além da observação hematológica de rotina, determinaram-se as concentrações de 2,3-difosfoglicerato e adenosinotrifosfato eritrocitários, lactato do sangue total, fosfato inorgânico plasmático, valor de P50 in vivo da ...

Dermatitis artefacta.

We report a case of a 29-year-old man presenting skin ulcerations on both sides of the mandible. The diagnosis of dermatitis artefacta was based on the morphology and evolution of the lesions, on the patient's borderline personality, on the objects found in his possession, and a later admission of having an involvement in the aggravation of the lesions. ; We report a case of a 29-year-old man presenting skin u...

Fluorescent products in the crystalline lens of type ii diabetic patients.

A body of evidence suggests that glycation of proteins and the resulting fluorescent products take part in the late complications of diabetes. The purpose of this study was to analyse the fluorescence of lens soluble proteins from diabetic patients. Soluble proteins were obtained from lens with cataract from 20 type II diabetic patients and from 21 non diabetic controls with similar age. The fluorescence of the...

Neurologic manifestations of Behçet disease. Review of the caseload of the Neur...

Neurological involvement in a series of patients with Behçet's disease, evaluated at the Departments of Neurology and Dermatology, St. Maria Hospital is reported. Meningoencephalytic or encephalytic were the most common clinical forms, while headache, cerebellar and pyramidal signs were the most prevalent symptoms/signs. On follow-up (range 2-13 years) the majority of the patients had either a progressive or a ...

Behçet's disease in Portugal.

During the last decades 156 patients with Behçet's disease were diagnosed and studied in Portugal. Until 1966 only two cases were referred in Portugal. In 1978 we reported 23 cases (18 males and 5 females) with multisystemic involvement, not different from that reported in other publications elsewhere. In 1987, 17 cases were reported from the Oporto region, diagnosed during a period of 5 years. In the region of...

Hemorheologic profile in patients with angina pectoris.

Abnormalities of erythrocyte filtrability in diabetic microangiopathy.