Encontrados 3 documentos, a visualizar página 1 de 1
Uma nova abordagem de cancro baseada na teoria das células estaminais
Martins, Filipe; Botelho, Maria; Cabrita, António; Freire-de-Oliveira, CarlosStem cells are being intensively studied because, in addition to therapeutic weapons, they can also be targets in treatment strategies of many diseases, namely in cancer, where they have an important etiologic role. Classical regulatory pathways of stem cells are deregulated in several tumours, strengthening the role of these cells in the carcinogenesis process. The mammary gland is a good model for studying ca...
Tratamento conservador do cancro da mama invasivo - avaliação de 11 anos
Custódio, Sofia; Saleiro, Sofia; Dias, Margarida; Freire-de-Oliveira, CarlosIntroduction: Breast conserving therapy involves conservative surgery – excision of the tumor mass with negative surgical margins – followed by post-operative radiation therapy. The objective of this study was to assess the clinical results of breast conserving therapy in invasive cancer. Study design: Retrospective observational study. Material and Methods: Analysis of 231 patients with invasive breast cancer ...
Carcinima de pequenas células do ovário do tipo hipercalcémico - Caso clínico
Domingues, Ana Patrícia; Marinho, Carol; Frutuoso, Cristina; Freire-de-Oliveira, CarlosSmall cell carcinoma of the ovary is a rare tumour that typically affects young women (mean age of 24 years). In two-thirds of cases it courses with hypercalcaemia and has a very reserved prognosis. Due to its rarity, optimal treatment is not consensual, but most 5-year survivors were submitted to a combination of surgery, adjuvant chemo and radiotherapy. The authors report a case of a 13 year old girl who pres...
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