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Topical caffeine delivery using biocellulose membranes: a potential innovative ...
Silva, N. H.; Drumond, I.; Almeida, I. F.; Costa, P.; Rosado, C. F.; Neto, C. P.; Freire, C. S.; Silvestre, A. J.In this study, biocellulose (BC) membranes have been investigated as caffeine topical delivery systems, for the potential treatment of cellulite. BC-caffeine membranes were prepared by a simple approach and the permeation of caffeine through human epidermis, from BC or from conventional formulation systems (solution and gel), was compared in vitro to assess their therapeutic applicability. Diffusion studies wit...
Bacterial cellulose membranes as transdermal delivery systems for diclofenac: I...
Silva, N. H.; Rodrigues, A. F.; Almeida, I. F.; Costa, P. C.; Rosado, C.; Neto, C. P.; Silvestre, A. J.; Freire, C. S.Bacterial cellulose (BC) membranes were explored as novel nanostructured transdermal delivery systems for diclofenac sodium salt (a typical non-steroidal anti-inflammatory drug). Diclofenac sodium salt loaded BC membranes were prepared through a simple methodology, using glycerol as plasticizer, and characterized in terms of structure, morphology and swelling behavior. The membranes were very homogeneous, quite...
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