In this study, biocellulose (BC) membranes have been investigated as caffeine topical delivery systems, for the potential treatment of cellulite. BC-caffeine membranes were prepared by a simple approach and the permeation of caffeine through human epidermis, from BC or from conventional formulation systems (solution and gel), was compared in vitro to assess their therapeutic applicability. Diffusion studies wit...
Bacterial cellulose (BC) membranes were explored as novel nanostructured transdermal delivery systems for diclofenac sodium salt (a typical non-steroidal anti-inflammatory drug). Diclofenac sodium salt loaded BC membranes were prepared through a simple methodology, using glycerol as plasticizer, and characterized in terms of structure, morphology and swelling behavior. The membranes were very homogeneous, quite...
OBJETIVO: Os cistos aracnoides são achados raros. Em 10% dos casos, sua localização é supraselar e ocorrem quase exclusivamente em crianças. Em geral, apresentam manifestações neurológicas e visuais, sendo incomum a puberdade precoce central como sinal clínico de sua presença. DESCRIÇÃO DO CASO: Menina avaliada aos dois anos e sete meses por telarca iniciada com um ano e oito meses e pubarca e axilarca com dois...
Propolis is a beehive product with a very complex chemical composition, widely used in folk medicine because of its several therapeutic activities. Its biological properties and chemical composition may vary according to the geografic location and to the different plant sources. Recently, we reported the mechanism for extration and propolis sample preparation (Falca˜o et al, Anal. Bioanal. Chem., 2010, 396: 887...
The study of botanical extracts used in traditional medicinal have always captured researchers attention. Propolis (bee glue) is a sticky dark-colored material that honeybees collected from parts of plants, buds and exudates, mix it with wax and other secretions and use it as construction and defense material in the hive. Because its biological and pharmacological properties, is extensively used in foods and be...
Propolis it is a natural resinous substance that honeybees (Apis melifera, L.) collect from buds and exudates of plants and transformed in the presence of bee enzymes. This substance plays an important role in the hive as a construction and defence material due to its chemical and biological properties.[1] Propolis composition is extremely complex and dependent on its vegetal source, geographical location and c...
This work outlines a characterization of the phenolic composition of the Azorean islands propolis. For that, eleven samples from S. Miguel and Terceira islands, were extracted and characterized. According to the I-IPLC analysis, an samples showed a similar phenolic profile, with 37 compounds identified by ESI-MS analysis and UV spectra. Although the samples revealed a close phenolic composition, significant dif...
Propolis is a resinous substance collected by honeybees from tree buds, comprising plant exudates, secreted substances from bee metabolism, pollen and waxes. This product is widely used in traditional medicine [I] and it has recently gained popularity as a health food supplement. Currently, it is extensively used in foods and beverages, and it is claimed to improve health and prevent diseases such as inflammati...
This research outlines an extensive characterization of the phenolic composition of a propolis sample from the northeast of Porto gal. For that, ao ethanolic extract was prepared, fractionated by HPLC and the identification of the phenolic compounds was done by electro spray mass spectrometry in the negative mode. This technical approach allowed the identification of 37 phenolic compounds in the Portoguese prop...
The antioxidant activity of five Agaricus sp. mushrooms was screened through chemical, biochemical and electrochemical techniques. The chemical assays allowed an evaluation of their reducing power and radical scavenging activity, while biochemical assays evaluated the lipid peroxidation inhibition capacity, using erythrocytes and brain cells as models; the electrochemical characterization of the mushrooms extra...
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