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Zoonotic potential of multidrug resistant Escherichia coli clonal groups in Por...
Jones-Dias, Daniela; Clemente, Lurdes; Manageiro, Vera; Themudo, Patrícia; Albuquerque, Teresa; Francisco, Ana Patrícia; Louro, DeolindaObjectives: Multidrug-resistant (MDR) plasmids together with clonal dissemination of resistant isolates are possibly the most successful combination of factors contributing to the spread of antibiotic resistance genes. Our aim was to identify clones associated with multidrug-resistance among human and dolphin isolates, in order to evaluate zoonotic potential and risk. Methods: Sixty two MDR human Escherichia co...
Accessing the molecular basis of transferable quinolone resistance in Escherich...
Caniça, Manuela; Jones-Dias, Daniela; Francisco, Ana Patrícia; Manageiro, Vera; Ferreira, EugéniaBackground: Salmonella and Escherichia coli resistant to quinolones frequently arise in animals, being easily transferred to humans through the food chain, which can ultimately lead to the development of untreatable infectious diseases. The aim of the present study was to investigate the presence of PMQR determinants among Salmonella spp and E. coli from food-producing animals and derivative food products. Meth...
Zoonotic potential of multidrug resistant Escherichia coli clonal groups in Por...
Jones-Dias, Daniela; Clemente, Lurdes; Manageiro, Vera; Themudo, Patrícia; Albuquerque, Teresa; Francisco, Ana Patrícia; Louro, DeolindaMultidrug-resistant (MDR) plasmids together with clonal dissemination of resistant isolates are possibly the most successful combination of factors contributing to the spread of antibiotic resistance genes. Our aim was to identify clones associated with multidrug-resistance among human and dolphin isolates, in order to evaluate zoonotic potential and risk. Sixty two MDR human Escherichia coli isolates were rand...
Epidemiology and zoonotic potential of Escherichia coli CTX-M-15-producing isol...
Caniça, Manuela; Clemente, Lurdes; Jones-Dias, Daniela; Manageiro, Vera; Themudo, Patrícia; Albuquerque, Teresa; Francisco, Ana PatríciaBackground: The recent spread of plasmid-located CTX-M-ESBL-encoding genes is a serious threat to the clinical efficacy of expanded-spectrum cephalosporins. This study proposes to identify the epidemiology of plasmid-mediated CTX-M-encoding genes between an Escherichia coli strain isolated from a dolphin and several E. coli strains of human origin and, explain the responsible mechanism and reservoirs of current...
Epidemiology of plasmid-mediated quinolone resistance determinants in bacterial...
Ferreira, Eugénia; Francisco, Ana Patrícia; Jones-Dias, Daniela; Manageiro, Vera; Caniça, ManuelaBackground: The use of (fluoro)quinolones both in humans and animals has contributed to the selection of resistant bacteria, limiting the agents available for treatment. This study aims to search for plasmid-mediated quinolone resistance (PMQR) determinants to give information about these expanding resistance mechanisms, their capacity of dissemination among different bacteria by mobile elements, and the role t...
Occurrence of plasmid-mediated quinolone resistance among bacteria isolated in ...
Ferreira, Eugénia; Clemente, Lurdes; Jones-Dias, Daniela; Francisco, Ana Patrícia; Manageiro, Vera; Themudo, Patrícia; Albuquerque, Teresa; Amado, AlicePoster P1359 ; Background: Plasmid-mediated quinolone resistance (PMQR) is increasingly identified worldwide in Enterobacteriaceae. The aim of this study was to evaluate the extension of PMQR in isolates from animals in Portugal. Methods: We screened 186 Enterobacteriaceae isolates for the presence of PMQR determinants, identified at National Laboratory of Veterinary Research (2008-2009). A total of 92 Salmone...
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