Encontrados 3 documentos, a visualizar página 1 de 1
Functional biopolymer-based matrices for modulation of chronic wound enzyme act...
Francesko, Antonio; da Costa, Diana Soares; Reis, R. L.; Pashkuleva, I.; Tzanov, TzankoCollagen, collagen/hyaluronic acid (HA) and collagen/HA/chitosan (CS) sponges loaded with epigallocatechin gallate (EGCG), catechin (CAT) and gallic acid (GA) were developed and evaluated as active chronic wound dressings. Their physico-mechanical properties, biostability, biocompatibility and ability to inhibit in vitro myeloperoxidase (MPO) and collagenase—major enzymes related with the persistent inflammatio...
GAGs-thiolated chitosan assemblies for chronic wounds treatment : control of en...
Francesko, Antonio; Costa, Diana Soares da; Lisboa, P.; Reis, R. L.; Pashkuleva, I.; Tzanov, TzankoMultilayered polyelectrolyte coatings comprising thiolated chitosan (TC) and glycosaminoglycans (GAGs), chondroitin sulphate and hyaluronic acid, were built using a layer-by-layer approach. The surface activity of these coatings for binding and inhibition of enzymes related to chronic inflammation, such as collagenase and myeloperoxidase, was assessed. The build-up of five bi-layers of TC/GAGs onto gold surface...
Thiolated chitosan/glycosaminoglycans multilayered films : QCM-D study on the f...
Francesko, Antonio; Díaz-Blanco, Carlos; Lisboa, P.; Costa, Diana Soares da; Pashkuleva, I.; Reis, R. L.; Tzanov, TzankoLayer-by-layer technique is widely used to produce polyelectrolyte multilayered films for material surface functionalization. The technique simplicity coupled with the biological potential of biopolymers, e.g. polysaccharides, make such assemblies a suitable choice for many biomedical applications. In this study the formation of the films comprising of thiolated chitosan and glycosaminoglycans (GAGs) by alterna...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||