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Enantiospecific 1,3-Dipolar Cycloadditions between Azadienophiles and 2-Phenyl-...

Ribeiro, Antonio; Alves, M. José; Sousa, Cristina; Fortes, A. Gil


Results of Endovascular Procedures Performed in Dysfunctional Arteriovenous Acc...

Machado, S; Ferreira, A; Lucas, C; Gil, C; Fortes, A; Neves, F

Aim. Percutaneous endovascular procedures have become the standard treatment of arteriovenous fistulae and graft stenosis. This study evaluates the immediate results of angiographic procedures performed by nephrologists in patients with dysfunctional arteriovenous fistulae and arteriovenous graft stenosis. Patients and Methods. A retrospective analysis was performed on patients referred to the three Interventio...


Synthesis of 2-n-benzyl carboxamide derivates of 1-azafagomine

Mendes, Raquel; Duarte, Vera C. M.; Fortes, A. Gil; Alves, M. José


1,3-dipolar cycloaddition of (2R,4aR,8aS)-2-phenyl-4,4a-dihydropyrano[3,2-d][1,...

Ribeiro, Antonio; Sousa, Cristina; Alves, M. José; Fortes, A. Gil


Asymmetric diels-alder reaction of tert-butyl 2H-azirine-3-carboxylate by a se...

Duarte, Vera C. M.; Faustino, H.; Salgueiro, D. A. L.; Fortes, A. Gil; Alves, M. José


Diastereo-selectivity of diels-alder cycloaddtions of erythrose benzylidene-ace...

Salgueiro, D. A. L.; Duarte, Vera C. M.; Alves, M. José; Fortes, A. Gil


Diastereo-selectivity in diels–alder cycloadditions of erythrose benzylidene-ac...

Salgueiro, D. A. L.; Duarte, Vera C. M.; Sousa, Cristina; Alves, M. José; Fortes, A. Gil

Maleimides were combined with D-erythrose benzylidene-acetal 1,3-butadienes 1 and 2 to study the facial selectivity of the Diels-Alder cycloadditions. The selectivity was found to be from moderate to good. The reaction diastereotopicity can be reversed with the temperature. Simultaneous coordination of diene 1, having a free hydroxyl group, and maleimide 3 to a chiral bimetallic Lewis acid catalyst (LACASA-DA r...


Diels-alder cycloaddition in the synthesis of 1-azafagomine, analogs, and deriv...

Salgueiro, D. A. L.; Sousa, Cristina; Fortes, A. Gil; Alves, M. José

This comprehensive review deals with the synthesis of 1-azafagomine, analogs, and derivatives having the Diels-Alder cycloaddition as the key step. Most of the compounds referred are racemic or have been resolved by lipase transesterification. There are two asymmetric cycloadditions leading to 1-azafagomine or to an analog. In one case both enantiomers of 1-azafagomine were prepared together with a pair of deri...


Advances in the synthesis of Homochiral (-)-1-azafagomine and (+)-5-epi-1-azafa...

Alves, M. José; Costa, Flora Teixeira e; Duarte, Vera C. M.; Fortes, A. Gil; Martins, J. A. R.; Micaelo, N. M.

- A new expeditious preparation of homochiral (-)-1-azafagomine, and (+)-5-epi-1-azafagomine has been devised. Stoodley´s diastereoselective cycloaddition of dienes bearing a 2,3,4,6-tetraacetyl glucosyl chiral auxiliary to 4-phenyl-1,2,4-triazole-3,5-dione, was merged with Bols protocol for functionalizing alkenes into molecules bearing a glucosyl framework. Homochiral (+)-5-epi-1-azafagomine was synthetized f...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia