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Crossroad between Inflammation, Iron and Lipids in Atherogenesis
Marques, Liliana; Lorenne, Robert; Auriac, Anne; Canonne-Hergaux, François; Costa, LucianaAtherosclerosis (ATH) is recognized as a chronic inflammatory condition and it is the leading cause of cardiovascular disease. The process of atherogenesis is characterized by the accumulation and oxidation of LDL (oxLDL) in the vessel wall and subsequent infiltration and activation of immune cells, particularly monocytes in an earlier stage and, later on, lymphocytes. The infiltrated monocytes differentiate in...
The effect of pro-inflammatory conditions on iron homeostasis and atherogenesis
Marques, Liliana; Robert, Lorenne; Auriac, Anne; Canonne-Hergaux, François; Costa, LucianaThis work was supported by National Institute of Health Dr Ricardo Jorge, I.P, INSERM (Institut National de la Santé et de la Recherche Médicale), CNRS (Centre National de la Recherche Scientifique), ANR (Agence Nationale de la Recherche, France; ANR- 08-GENO-000) , Fundação para a Ciência e Tecnologia (Grant SFRH/BD/48671/2008) and BioFIG (B Center for Biodiversity, Functional and Integrative Genomics). ; Ath...
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