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On the use of dexamethasone-loaded liposomes to induce the osteogenic different...
Monteiro, Nelson; Martins, Albino; Ribeiro, Diana Margarida da Costa; Faria, Susana, 1972-; Fonseca, Nuno A.; Moreira, João N.; Reis, R. L.Stem cells have received considerable attention by the scientific community because of their potential for tissue engineering and regenerative medicine. The most frequently used method to promote their differentiation is supplementation of the in vitro culture medium with growth/differentiation factors (GDFs). The limitations of that strategy caused by the short half-life of GDFs limit its efficacy in vivo and ...
Immobilization of bioactive factor-loaded liposomes at the surface of electrosp...
Monteiro, Nelson; Martins, Albino; Pires, R. A.; Faria, Susana, 1972-; Fonseca, Nuno A.; Moreira, João N.; Reis, R. L.; Neves, N. M.Publicado em "Journal of Tissue Engineering and Regenerative Medicine", vol. 7, supp. 1 (2013) ; The ability to manipulate and control the surface properties is of crucial importance in the designing of scaffolds for Tissue Engineering (TE) and Regenerative Medicine. Electrospun nanofibers (NFM), due to their morphology and fibrous structure have received much attention as potential biomedical devices, TE scaf...
Induction of human mesenchymal stem cells osteogenesis by bioactive agent-relea...
Monteiro, Nelson; Martins, Albino; Ribeiro, Diana Margarida da Costa; Faria, Susana, 1972-; Fonseca, Nuno A.; Moreira, João N.; Reis, R. L.Stem cell therapy is a rapidly evolving area of research in regenerative medicine. Mesenchymal stem cells (MSCs) have received considerable attention by the scientific community because of their potential of expansion and the ability to differentiate into various mesodermal tissues. Liposomes are well-established non-viral carrier systems, presenting significant advantages over other nanoparticle-based drug del...
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