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Activation of the endoplasmic reticulum stress response by the amyloid-beta 1–4...
Fonseca, Ana Catarina R. G.; Ferreiro, Elisabete; Oliveira, Catarina R.; Cardoso, Sandra M.; Pereira, Cláudia F.Neurovascular dysfunction arising from endothelial cell damage is an early pathogenic event that contributes to the neurodegenerative process occurring in Alzheimer's disease (AD). Since the mechanisms underlying endothelial dysfunction are not fully elucidated, this study was aimed to explore the hypothesis that brain endothelial cell death is induced upon the sustained activation of the endoplasmic reticulum ...
Data: 2013
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Origem: Estudo Geral - Universidade de Coimbra
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