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Perspectives for using light quality knowledge as an advanced ecophysiological ...
Merotto Jr.,A.; Fischer,A.J.; Vidal,R.A.The current knowledge of light quality effects on plant morphogenesis and development represents a new era of understanding on how plant communities perceive and adjust to available resources. The most important consequences of light quality cues, often mediated by decreasing in red far-red ratios with respect to the spectral composition of incident sunlight radiation, affecting weed-crop interaction are the in...
Mutations in STAT3 and IL12RB1 impair the development of human IL-17 – producin...
Beaucoudrey, L.; Puel, A.; Filipe-Santos, O.; Cobat, A.; Ghandil, P.; Chrabieh, M.; Feinberg, J.; Bernuth, H.; Samarina, A.; Jannière, L.; Fieschi, C.Abstract The cytokines controlling the development of human interleukin (IL) 17--producing T helper cells in vitro have been difficult to identify. We addressed the question of the development of human IL-17--producing T helper cells in vivo by quantifying the production and secretion of IL-17 by fresh T cells ex vivo, and by T cell blasts expanded in vitro from patients with particular genetic traits affecting...
Imunodeficiência primária por défice de ZAP-70
Barata, LT; Henriques, R; Hivroz, C; Jouanguy, E; Paiva, A; Freitas, AM; Coimbra, HB; Fischer, A; Carmona da Mota, HThe authors present the case of a child with recurrent infections since the age of 4 months, including bilateral pneumonia by Pneumocystis carinii and protracted varicella. Serum immunoglobulin values (when 10 months old), and B cell values were normal. There was persistent lymphocytic leucocytosis, near absence of CD8+ cells, and an increased CD4/CD8 ratio. The percentage of activated T cells and the expressio...
A block active set algorithm for large-scalequadratic programming with box cons...
Fernandes, L.; Fischer, A.; Júdice, J.; Requejo, C.; Soares, J.Abstract An algorithm for computing a stationary point of a quadratic program with box constraints(BQP) is proposed. Each iteration of this procedure comprises a guessing strategy whichforecasts the active bounds at a stationary point, the determination of a descent direction bymeans of solving a reduced strictly convex quadratic program with box constraints and anexact line search. Global convergence is estab...
Prevention of bone marrow graft failure by an anti LFA-1 monoclonal antibody
Fischer,A.; Blanche,S.; Le Deist,F.; Veber,F.; Griscelli,C.; Olive,D.; Delaage,M.; Mawas,C.Graft rejection is the major cause of failure of HLA mismatched bone marrow transplantation because of residual host immunity. we have proposed to use a monoclonal murine antibody specific for the LFA-1 molecule (25-3) to prevent graft failure in HLA mismatched bone marrow transplantation (BMT). The rationale for this approach is three fold: LFA-1 deficient patients (3/3) do not reject HLA mismatched BMT; anti ...
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