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Anti-inflammatory activity of Cymbopogon citratus leaves infusion via proteasom...

Francisco, Vera; Costa, Gustavo; Figueirinha, Artur; Marques, Carla; Pereira, Paulo; Neves, Bruno Miguel; Lopes, Maria Celeste; García-Rodríguez, Carmen

Ethnopharmacological relevance Cymbopogon citratus (DC.) Stapf leaves infusion is used in traditional medicine for the treatment of inflammatory conditions, however little is known about their bioactive compounds. Aim of the study Investigate the compounds responsible for anti-inflammatory potential of Cymbopogon citratus (Cy) on cytokines production induced by lipopolysaccharide (LPS) in human and mouse macro...


Cymbopogon citratus as source of new and safe anti-inflammatory drugs: Bio-guid...

Francisco, Vera; Figueirinha, Artur; Neves, Bruno Miguel; García-Rodríguez, Carmen; Lopes, Maria Celeste; Cruz, Maria Teresa; Batista, Maria Teresa

Ethnopharmacological relevance Aqueous extracts of Cymbopogon citratus (Cy) leaves are used in traditional medicine for the treatment of inflammatory conditions, however, little is known about their mechanism of action. Aim of the study The aim of this study is to explore the anti-inflammatory properties of Cymbopogon citratus leaves and their polyphenol-rich fractions (PFs), as well its mechanism of action i...


Spectroscopic Study of the Hydration Equilibria and Water Exchange Dynamics of ...

Yerly, Fabrice; Dunand, Frank A.; Tóth, Éva; Figueirinha, Artur; Kovács, Zoltán; Sherry, A. Dean; Geraldes, Carlos F. G. C.; Merbach, André E.

The hydration state of a series of [Ln(DO2A)(H2O)n]+ complexes in aqueous solution at pH = 6.4-7.0 was studied by measuring the lanthanide-induced 17O shifts (LIS) of water [Ln includes elements from Ce to Yb; DO2A = 1,7-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecane]. Their contact contribution, obtained from Reilley plots, indicated a decrease in the inner-sphere water coordination number of the [Ln(DO2A)(...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia