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NOD2 gene mutations in ulcerative colitis: useless or misunderstood?

PURPOSE: NOD2 mutations have been linked to an increased risk of Crohn's disease and to some of its phenotypes. The association between NOD2 mutations and susceptibility to ulcerative colitis (UC) remains somewhat controversial and potential correlations between these mutations and UC phenotype have not been studied. AIM: To assess whether NOD2 mutations are a risk factor for UC in Portugal and if there are any...

The 1909 Benavente (Portugal) earthquake : search for the source

The Lower Tagus River Valley has been affected by severe earthquakes comprising distant events, as in 1755, and local earthquakes, as in 1344, 1531, and 1909. The 1909 earthquake was located NE of Lisbon, near Benavente, causing serious damage and many losses. Mw 6.0 has been assessed for this earthquake and a reverse faulting focal mechanism solution has been calculated. Poor epicenter location, possible di...

Automatic polyp detection in pillcam colon 2 capsule images and videos: prelimi...

Background. The aim of this work is to present an automatic colorectal polyp detection scheme for capsule endoscopy. Methods. PillCam COLON2 capsule-based images and videos were used in our study. The database consists of full exam videos from five patients. The algorithm is based on the assumption that the polyps show up as a protrusion in the captured images and is expressed by means of a P-value, defined by ...

Rare cause of fever in a patient with ulcerative colitis

Síndrome de Sweet: a propósito de um caso clínico

A associação da síndrome de Sweet e doença de Crohn é conhecida, embora rara, sendo considerada uma manifestação extra-intestinal da doença. É descrito um caso desta dermatose neutrofílica num homem de 65 anos com antecedentes de espondilite anquilosante e doença de Crohn, sob terapêutica imunossupressora, que inicia subitamente febre, artralgias e exantema papular eritemato-violáceo disseminado. Analiticamente...

Performance of stones under different conditions : a study of metro stations

Contributos da biomecânica para o estudo do rendimento desportivo em natação

A coupled convection-diffusion level set model for tracking epithelial cells in...

Colorectal cancer is initiated in colonic crypts as a consequence of alterations leading to the disruption of the normal colonic cellular process. We propose a model, which couples a convection-diffusion type equation with a level set equation, for tracking the time evolution of an epithelial cell set, inside a colonic crypt, until it reaches the top of the crypt. The convection-diffusion equation describes the...

Small-bowel capsule endoscopy in patients with suspected Crohn's disease-diagno...

Background. The aim of this work was to assess the value of capsule enteroscopy in the diagnosis of patients with suspected Crohn's Disease (CD). Methods. This was a retrospective study in a single tertiary care centre involving patients undergoing capsule enteroscopy for suspected CD. Patients taking nonsteroidal anti inflammatory drugs during the thirty preceding days or with a follow-up period of less than s...

CARD15 Mutations and Colorectal Cancer in a South European Country