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Estrutura e dinâmica do tecido ósseo

Judas, F; Palma, P; Falacho, RI; Figueiredo, H

O tecido ósseo é uma forma especializada de tecido conjuntivo constituído por uma fase mineral, formada essencialmente por cristais de fosfato de cálcio, sob a forma de hidroxiapatite, que assenta numa organizada matriz colagénica. A combinação da fase mineral e da fase orgânica confere ao tecido ósseo propriedades únicas, que o tornam muito resistente às solicitações mecânicas. Apesar seu aspeto aparentemente...


Factores preditivos da aderência dos pais a um programa de seguimento de crianç...

Marecos, C; Oliveira, A; Figueiredo, H; Cadete, A; Cunha, M

Introduction: Newborn infants of very low birth weight (VLBW) are at high risk of neurodevelopment disorder, justifying the implementation of early intervention programs for these children. Objectives: Evaluate the effects of long-term "Care Programme for Development” (CPD) applied to VLBW infants, analyze parents' compliance to follow-up and identify perinatal variables with influence on neurodevelopment. Meth...


Effect of the calcination temperature on the composition and microstructure of ...

Figueiredo, M; Fernandes, A; Martins, G; Freitas, J; Judas, F; Figueiredo, H

The present work focus the study of cortical bone samples of different origins (human and animal) subjected to different calcination temperatures (600, 900 and 1200 °C) with regard to their chemical and structural properties. For that, not only standard techniques such as thermogravimetric analysis, Fourier transform infrared spectroscopy, X-ray diffraction and scanning electron microscopy were used but also me...


Physicochemical characterization of biomaterials commonly used in dentistry as ...

Figueiredo, M; Henriques, J; Martins, G; Guerra, F; Judas, F; Figueiredo, H

The present work focuses on the physicochemical characterization of selected mineral-based biomaterials that are frequently used in dental applications. The selected materials are commercially available as granules from different biological origins: bovine, porcine, and coralline. Natural and calcined human bone were used for comparison purposes. Besides a classical rationalization of chemical composition and c...



Dual use of Diff-Quik-like stains for the simultaneous evaluation of human sper...

Sousa, AP; Tavares, RS; Velez de la Calle, JF; Figueiredo, H; Almeida, V; Almeida-Santos, T; Ramalho-Santos, J

BACKGROUND: Sperm chromatin status and nuclear DNA damage can be detected using well-established assays. However, most techniques are time-consuming and/or involve elaborate protocols and equipment. We have recently developed a simple and fast method to monitor sperm chromatin status in field conditions using the Diff-Quik assay which is employed in fertility clinics to assess sperm morphology with standard bri...


Novos desafios da técnica na transplantação de órgãos

Figueiredo, H.

As células estaminais são conhecidas há já algumas décadas, mas só recentemente se adquiriu o conhecimento suficiente que permitiu o seu crescimento fora do organismo, in vitro, por longos períodos de tempo. No que respeita à sua localização no organismo, os principais tipos de células estaminais são: as do embrião, as da linha germinal de fetos e as de alguns órgãos do indivíduo adulto. Apesar de todos os avan...


Nutritive sucking pattern from very low birth weight preterm to term newborn

Cunha, M; Barreiros, J; Gonçalves, I; Figueiredo, H

The contribution of maturation and stimulation to the development of oral feeding was investigated, with two main objectives: (1) to analyze the nutritive sucking pattern of very-low-birth-weight newborns from their first oral feeding to the acquisition of independent oral feeding, and (2) to compare the nutritive sucking patterns of these babies, after feeding autonomy, with healthy term newborns. METHODS: Two...


Evaluating structural differences in cortical bone tissue after demineralizatio...

Martins, G; Freitas, J; Judas, F; Trindade, B; Figueiredo, H

Although the best results in bone grafting have been achieved with autogeneuos bone tissue, allografts and xenografts have been widely used either in mineralized, demineralized, or calcined forms. Demineralized bone has been proven to stimulate new bone formation by exposing, proteins and growth factors necessary for osteoinduction. On the other hand, calcined bone offers a natural architectural mineralized mat...



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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia