Encontrados 5 documentos, a visualizar página 1 de 1
Endoscopic Mucosal Resection of Superficial Colorectal Neoplasms: Review of 140...
Serrano, Miguel; Mão de Ferro, Susana; Fidalgo, Paulo; Lage, Pedro; Chaves, Paula; Dias Pereira, AntónioIntroduction and Aims: Endoscopic mucosal resection (EMR) has been shown to be useful in the removal of large colorectal sessile and flat lesions, avoiding the need for surgical resection. The aim of this study was to evaluate the efficacy and safety of EMR in colorectal lesions using the inject-and-cut technique. Material and Methods: Based on the review of colonoscopy reports, performed from February 2007 and...
Evolucionismo celular: Uma Viagem Imaginária de Darwin à Clínica Oncológica
Fidalgo, Paulo; Serviço de Gastrenterologia do IPOFG.
Risk of colorectal cancer associated with the C677T polymorphism in 5,10-methyl...
Guerreiro, Catarina Sousa; Carmona, Bruno; Gonçalves, Susana; Carolino, Elisabete; Fidalgo, Paulo; Brito, Miguel; Leitão, Carlos Nobre; Cravo, MaríliaBackground: Polymorphisms located in genes involved in the metabolism of folate and some methyl-related nutrients are implicated in colorectal cancer (CRC). Objective: We evaluated the association of 3 genetic polymorphisms [C677T MTHFR (methylene tetrahydrofolate reductase), A2756G MTR (methionine synthase), and C1420T SHMT (serine hydroxymethyltransferase)] with the intake of methyl-donor nutrients in CRC ris...
MYH associated polyposis: severe phenotype in the homozygosity for the 1103delC...
De Ferro, Susana Mão; Lage, Pedro; Suspiro, Alexandra; Fidalgo, Paulo; Fragoso, Sofia; Baltazar, Célia; Vitoriano, Inês; Rodrigues, PaulaMYH-associated polyposis (MAP) is an autosomal recessive disease associated with multiple colonic adenomas and colorectal cancer. Y165C and G382D MYH missense mutations are involved in more than 80% of cases in Caucasians and the large series published do not include patients homozygous for other mutations. We present the report of two siblings homozygous for the nonsense frameshift mutation 1103delC. The proba...
The D1822V APC polymorphism interacts with fat, calcium, and fiber intakes in m...
Guerreiro, Catarina Sousa; Cravo, Marília; Brito, Miguel; Vidal, Pedro L.; Fidalgo, Paulo O.; Leitão, Carlos NobreBackground - Both genetic and environmental factors affect the risk of colorectal cancer (CRC). Objective - We aimed to examine the interaction between the D1822V polymorphism of the APC gene and dietary intake in persons with CRC. Design - Persons with CRC (n = 196) and 200 healthy volunteers, matched for age and sex in a case-control study, were evaluated with respect to nutritional status and lifestyle facto...
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