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Hyaluronic acid/poly(amidoamine) dendrimer nanoparticles for central nervous sy...
Silva, Barbara L.; Cerqueira, Susana R.; Fevereiro, J. P.; Pirraco, R. P.; Marques, A. P.; Oliveira, Joaquim M.; Reis, R. L.; Sousa, NunoCentral nervous system (CNS) disorders are among the diseases with less efficiency in treatment. In order to reach its target and exert its effect within the brain parenchyma, drugs must overcome the blood brain barrier (BBB) and the blood-cerebrospinal fluid-brain (BCSFB). The aim of this work was to develop a novel nano-based dendrimer which could serve as a nanocarrier with the ability to cross these barri- ...
Data: 2012
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Origem: RepositóriUM - Universidade do Minho
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