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Investigation of the in vivo genotoxic effects of a titanium dioxide nanomateri...
Louro, Henriqueta; Tavares, Ana; Vital, Nádia; Costa, Pedro; Alverca, Elsa; Zwart, Edwin; de Jong, Wim H.; Fessard, Valérie; Lavinha, JoãoTitanium dioxide nanomaterials (TiO2) are increasingly used in a diversity of products, including cosmetics, pharmaceuticals, food and inks, which contrasts with the existing uncertainties in respect to their risks for human and environment health. Previous studies on the genotoxicity of TiO2 reported discrepant findings, both in cellular and organismal systems. In a recent work, we showed that some nanosized T...
In vitro testing strategy for nanomaterials including database (Deliverable 5):...
Norppa, Hannu; Siivola, Kirsi; Fessard, Valérie; Tarantini, Adeline; Apostolova, Margarita; Jacobsen, Nicklas Raun; Wallin, Håkan; Goetz, Mario E.WP5 had two objectives: - To generate in vitro genotoxicity data on manufactured MNs (specific objective #3). - To perform a round robin test on in vitro genotoxicity testing of MNs (specific objective #4) WP5 addressed the basic questions of in vitro genotoxicity testing of manufactured nanomaterials (MNs): how well in vitro assays can be used for revealing the genotoxic potential of MNs, which assays are suit...
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