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Electrochemical measurement of endogenously produced nitric oxide in brain slic...

Ferreira, Nuno R.; Ledo, Ana; Frade, João G.; Gerhardt, Greg A.; Laranjinha, João; Barbosa, Rui M.

The role of nitric oxide (NO) as a regulatory diffusible molecule in the brain requires the evaluation of its concentration dynamics. In this work, we have developed microelectrodes suitable for real time electrochemical measurements of NO in vitro. Nafion and o-phenylenediamine were used to modify the surface of carbon fiber microelectrodes (8 [mu]m diameter; [approximate]100 [mu]m tip length). Coating with Na...


Reduction of Rat Pleural Microvilli Caused by Noise Pollution

Maria João R. Oliveira; António S. Pereira; Paula G. Ferreira; Nuno R. Grande; Artur P. Águas; Laura Guimarães; Diamantino Freitas; A Carvalho

Scanning electron microscopy (SEM) was used to investigate whether chronic exposure to noise modifies pleural morphology. Rats were submitted to 8-h/day schedule of noise that is similar to the working hours at cotton-mill rooms. Morphometry of the area occupied by microvilli on the pleural surface showed a decrease in microvilli after 3 months of rat exposure to noise. The reduction of microvilli was 10% after...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia