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New dextrin nanomagnetogels as contrast agents for magnetic resonance imaging
Gonçalves, C.; Lalatonne, Y.; Melro, L.; Badino, G.; Ferreira, M. F. M.; David, L.; Geraldes, C. F. G. C.; Motte, L.; Martins, J. A.; Gama, F. M.This study aims at the production and characterization of a “nanomagnetogel” consisting of superparamagnetic iron oxide nanoparticles (g-Fe2O3) stabilized within a hydrophobized-dextrin nanogel. The nanomagnetogel obtained was extensively characterized with respect to physico-chemical (transmission electron microscopy, cryo-scanning electron microscopy, dynamic light scattering, small angle X-ray scattering), m...
New dextrin nanomagnetogels as contrast agents for magnetic resonance imaging
Gonçalves, Catarina; Lalatone, Y.; Melro, Liliana Sofia da Silva Ferreira Pinto; Badino, G.; Ferreira, M. F. M.; David, L.; Geraldes, C. F. G. C.This study aims at the production and characterization of a “nanomagnetogel” consisting of superparamagnetic iron oxide nanoparticles (γ-Fe2O3) stabilized within a hydrophobized-dextrin nanogel. The nanomagnetogel obtained was extensively characterized with respect to physico-chemical (transmission electron microscopy, cryo-scanning electron microscopy, dynamic light scattering, small angle X-ray scattering), m...
Studies on the biodistribution of dextrin nanoparticles
Gonçalves, Clarisse; Ferreira, M. F. M.; Santos, A. C.; Prata, M. I. M.; Martins, J. A.; Geraldes, Carlos F. G. C.; Gama, F. M.The characterization of biodistribution is a central requirement in the development of biomedical applications based on the use of nanoparticles, in particular for controlled drug delivery. The blood circulation time, organ biodistribution and rate of excretion must be well characterized in the process of product development. In this work, the biodistribution of recently developed self-assembled dextrin nanopar...
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