Encontrados 6 documentos, a visualizar página 1 de 1
Antioxidant capacity and toxicological evaluation of pterospartum tridentatum f...
Ferreira, Fernanda M.; Dinis, Lia T.; Azedo, Pedro; Galhano, Cristina; Cardoso, Susana M.; Domingues, M.R.M.; Pereira, Olívia R.; Simões, AnabelaPterospartum tridentatum Willk. (prickled broom) is an autochthonous plant, common in Portuguese territory. The yellow flowers are used in traditional medicine, as a potential cure for all body illnesses, mainly for throat irritation treatment or for diabetes, hypertension and hypercholesterolemia therapy.Despite its traditional use, no toxicological assessment has been performed as we know. A high antioxidant ...
Toxicological evaluation of pterospartum tridentatum flower water
Ferreira, Fernanda M.; Cardoso, Susana M.; Pereira, Olívia R.; Domingues, M.R.M.; Azedo, Pedro; Dinis, Lia T.; Peixoto, Francisco P.Pterospartum tridentatum Willk. (prickled broom) is an autochthonous plant, common in Portuguese territory. The yellow flowers are widely used in traditional medicine, as a potential cure for all body illnesses, mainly for throat irritation treatment or for diabetes, hypertension and hypercholesterolemia therapy. Despite its wide traditional use, no toxicological assessment of this plant has been performed, as ...
Mitochondrial Bioenergetics, Diabetes, and Aging: Top-Down Analysis Using the D...
Ferreira, Fernanda M.; Moreno, António J.; Seiça, Raquel; Santos, Maria S.; Palmeira, Carlos M.In the present study we investigated the changes in the oxidative phosphorylation system of liver mitochondria, isolated from diabetic Goto-Kakizaki (GK) and Wistar (control) rats with different ages (6, 12, 26, and 52 weeks). We used a kinetic approach known as “top-down” analysis, which conceptually divides the oxidative phosphorylation system into two subsystems: one producing the protonmotive force (Δp) and...
Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mi...
Oliveira, Paulo J.; Seica, Raquel; Santos, Dario L.; Rolo, Anabela P.; Sardao, Vilma A.; Ferreira, Fernanda M. L.; Palmeira, Carlos M.; Santos, Maria S.The heart is one of the organs affected during the later stages of diabetes. Mitochondrial function has already been proposed to be affected during the course of diabetes. Nevertheless, little information is known concerning the impact of antioxidants in heart mitochondria of a milder model for diabetes, such as the Goto-Kakizaki (GK) rat, where mitochondrial function appears ameliorated. The objective of this ...
Diabetes induces metabolic adaptations in rat liver mitochondria: role of coenz...
Ferreira, Fernanda M.; Seiça, Raquel; Oliveira, Paulo J.; Coxito, Pedro M.; Moreno, António J.; Palmeira, Carlos M.; Santos, Maria S.Several studies have been carried out to evaluate the alterations in mitochondrial functions of diabetic rats. However, results are sometimes controversial, since experimental conditions diverge, including age and strain of used animals. The purpose of this study was to evaluate the metabolic modifications in liver mitochondria, both in the presence of severe (STZ-treated rats) and mild hyperglycaemia [Goto-Kak...
Diabetes and mitochondrial bioenergetics: Alterations with age
Ferreira, Fernanda M.; Palmeira, Carlos M.; Seiça, Raquel; Moreno, António J.; Santos, Maria S.Several studies have been carried out to evaluate the alterations in mitochondrial functions of diabetic rats. However, some of the results reported are controversial, since experimental conditions, such as aging, and/or strain of animals used were different. The purpose of this study was to evaluate the metabolic changes in liver mitochondria, both in the presence of severe hyperglycaemia (STZ-treated rats) an...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||