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Gut permeability to lactulose and mannitol differs in treated Crohn's disease a...

Vilela,E.G.; Torres,H.O.G.; Ferrari,M.L.A.; Lima,A.S.; Cunha,A.S.

The gut barrier monitors and protects the gastrointestinal tract from challenges such as microorganisms, toxins and proteins that could act as antigens. There is evidence that gut barrier dysfunction may act as a primary disease mechanism in intestinal disorders. The aim of the present study was to evaluate the barrier function towards sugars after the appropriate treatment of celiac disease and Crohn's disease...

Data: 2008 | Origem: OASIS br

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Recurrent ATP1A2 mutations in Portuguese families with familial hemiplegic migr...

Castro, M.; Stam, A.; Lemos, C.; Barros, J.; Gouveia, R.; Martins, I.; Koenderink, R.; Vanmolkot, K.; Mendes, A.; Frants, R.; Ferrari, M.; Sequeiros, J.

Familial hemiplegic migraine is a rare autosomal dominant subtype of migraine with aura. Three genes have been identified, all involved in ion transport. There is considerable clinical variation associated with FHM mutations. Genotype-phenotype correlation studies are needed, but are challenging mainly because the number of carriers of individual mutations is low. One exception is the recurrent T666M mutation i...

Data: 2007 | Origem: Repositório Científico do Centro Hospitalar do Porto

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Theoretical and experimental study of the effects of scale-up on mixing time fo...

Bonvillani,P.; Ferrari,M. P.; Ducrós,E. M.; Orejas,J. A.

Mixing time is one of the criteria most widely used to characterize mixing intensity in bioprocesses. In bioreactors, mixing mainly depends on amount of energy consumed, reactor and stirrer shapes, airing speed and the rheology of the medium. In this work we experimentally determined the mixing times for a lab-scale bioreactor equipped with a stirrer propelled by two Rushton turbines. From these experiments we ...

Data: 2006 | Origem: OASIS br

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