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Regulation mechanisms of bone metabolism.

The bone is continuously in a remodelling process. Bone mass is maintained in a continuous balance between its destruction and formation. Bone remodelling proceeds in a highly regulated cycle in which osteoclasts adhere to bone and subsequently remove it by acidification and proteolytic digestion and the osteoblasts secrete a organic matrix which is calcified into new bone. Bone remodelling is the cellular basi...