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Body Fat Percentage Is a Major Determinant of Total Bilirubin Independently of ...

Belo, L; Nascimento, H; Kohlova, M; Bronze-da-Rocha, E; Fernandes, J; Costa, E; Catarino, C; Aires, L; Mansilha, HF; Rocha-Pereira, P; Quintanilha, A

OBJECTIVES: Bilirubin has potential antioxidant and anti-inflammatory properties. The UGT1A1*28 polymorphism (TA repeats in the promoter region) is a major determinant of bilirubin levels and recent evidence suggests that raised adiposity may also be a contributing factor. We aimed to study the interaction between UGT1A1 polymorphism, hematological and anthropometric variables with total bilirubin levels in you...

Data: 2014   |   Origem: Repositório Comum

Ventilação Mecânica numa Unidade de Cuidados Intensivos Pediátricos

M., Santos; A., Macedo; M. C., Vale; A., Marques; I., Fernandes; J., Estrada; J., Ramos; L., Ventura; R., Valente; D., Barata; C., Vasconcelos

Os autores fazem a análise dos doentes submetidos a ventilação mecânica na Unidade de Cuidados Intensivos Pediátricos do Hospital de Dona Estefânia, num período de 33 meses, desde a sua abertura em Abril de 1991 até ao final de Dezembro de 1993.Neste período foram internadas na Unidade 1513 crianças, das quais 264 (17.4%) foram ventiladas.A idade dos doentes ventilados variou entre os 28 dias e os 15 anos (médi...

Data: 2014   |   Origem: Acta Pediátrica Portuguesa

Sr and Nd isotope data for arc-related (meta) volcanics (SW Iberia)

Santos, J. F.; Mata, J.; Ribeiro, S.; Fernandes, J.; Silva, J.

In the southern sector of the Ossa-Morena Zone (Iberian Variscan Chain), along its boundaries with the Beja-Acebuches Ophiolite and the South-Portuguese Zone, Upper Palaeozoic igneous mafic and intermediate rocks, both intrusive and extrusive, are widely represented. The so-called Odivelas Unit (Andrade,1983), include (meta-) basalts and (meta-) andesites, which, according with previous studies, display low-K ...


PHB-PEO electrospun fiber membranes containing chlorhexidine for drug delivery ...

Fernandes, J. G.; Correia, D. M.; Botelho, G.; Padrão, J.; Ribeiro, C.; Lanceros-Mendez, S.; Sencadas, V.

Fiber meshes of poly(hydroxybutyrate) (PHB) and poly(hydroxybutyrate)/ poly(ethylene oxide) (PHB/PEO) with different concentrations of chlorhexidine (CHX) were prepared by electrospinning, for assessment as a polymer based drug delivery system. The electrospun fibers were characterized at morphological, molecular and mechanical levels. The bactericidal potential of PHB and PHB/PEO electrospun fibers with and wi...

Data: 2013   |   Origem: CiencIPCA

Erlotinib in non-small-cell lung cancer patients from Hospital Fernado Fonseca

Fernandes, J; Frade, P; Teixeira, S; Afonso, R

INTRODUTION: The oral epidermal growth factor receptor (EGFR) tyrosine-kinase inibitor (TKI) erlotinib is an established second-line treatment for advanced non-small-cell lung cancer (NSCLC).1 Erlotinib delays disease progression and increases survival after first-line chemotherapy in patients with advanced NSCLC as second-line therapy.2 Maintenance therapy with erlotinib, when compared to placebo, could be ass...


Raman Amplifiers for Use in WDM Systems

D. B. M. Pereira; A. L. J. Teixeira; M. J. N. Lima; P. S. B. André; H. C. C. Fernandes; J. R. Ferreira da Rocha

In this paper Raman Amplifiers (RAs) for Wavelength Division Multiplexed (WDM) fiber optic systems are analysed. We start by explaining the physical principles of this kind of amplification are explained, and the principal characteristics and advantages of using these amplifiers are enumerated.The technique of multiple pumping (MP) is studied aiming to obtain broadband amplifiers w...

Data: 2012   |   Origem: Electrónica e Telecomunicações

Electroluminescence yield in xenon gas detectors

C.M.B. Monteiro; L.M.P. Fernandes; J.A.M. Lopes; L.C.C. Coelho; J.F.C.A. Veloso; J.M.F.dos Santos; K. Giboni; E. Aprile

The electroluminescence yield was studied for xenon gas as a function of the electric field in the scintillationregion, for room temperature using a gas proportional scintillation counter. A large area avalanche photodiode was used for the readout of the VUV secondary scintillation produced in the gas, together with the 5.9-keV x-rays directly absorbed in the photodiode. Using the latter as a reference for the ...

Data: 2012   |   Origem: Electrónica e Telecomunicações

Mechanical properties of sintered La9.33Si2Ge4O26 oxyapatite materials for SOFC...

Santos, Miguel; Alves, Cátia; Oliveira, F. A. Costa; Marcelo, Teresa; Mascarenhas, João; Fernandes, J.V.; Trindade, B.

Mechanical properties of La9.33Si2Ge4O26 prepared by mechanical alloying and subsequent sintering at 1300–1400 °C for 1 h were evaluated. Hardness and Young's modulus values in the range 7.3–9.6 GPa and 106–135 GPa, respectively, were obtained from nanohardness tests. The fracture toughness values derived from the Palmqvist method varied between 3.5 and 3.9 MPa m1/2 from classical microindentation test with an ...

Data: 2012   |   Origem: Repositório do LNEG

Carta geoambiental da região da Grande Beira, Mozambique, escala 1:50.000

Quental, Lídia Maria; Ramalho, Elsa Cristina; Daudi, Elias X.; Batista, Maria João; Fernandes, J.; Milisse, Dino; Dias, Ruben P.; Oliveira, José Tomás

Data: 2012   |   Origem: Repositório do LNEG

Posterior nutcracker syndrome with left renal vein duplication: a rare cause of...

Preza-Fernandes, J.; Amorim, R.; Gomes, M.; Oliveira, V.; Reis, A.; Ribeiro-Castro, J.

Abstract The nutcracker syndrome (NCS) is a rare cause of haematuria. It embraces an extended nonpathognomonic spectrum of symptoms that imply a difficult diagnosis. Ultimately it may be associated with substantial morbidity and even life-threatening events. We report a rare cause if a 12-year-old boy who presented with a history of frequent intermittent episodes of painless constant haematuria. The cystoscopy ...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia