Encontrado 1 documento, a visualizar página 1 de 1
Ordenado por
Data
ir para a página:
1
Electrochemical detection of in situ adriamycin oxidative damage to DNA
Oliveira-Brett, A. M.; Vivan, M.; Fernandes, I. R.; Piedade, J. A. P.Adriamycin intercalation and in situ interaction with double helix DNA was investigated using a voltammetric DNA-biosensor. Oxidation and reduction of adriamycin molecules intercalated in double helix DNA were investigated in order to understand the in vivo mechanism of action with this anti-neoplasic drug. The results showed that the interaction of adriamycin with DNA is potential-dependent causing contact bet...
Data: 2002
|
Origem: Estudo Geral - Universidade de Coimbra
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||