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Neuromuscular transmission modulation by A2A adenosine receptors in the SOD1G93...

Tese de mestrado, Neurociências, Faculdade de Medicina, Universidade de Lisboa, 2013 ; Amyotrophic Lateral Sclerosis (ALS) is an adult-onset progressive neurodegenerative disease characterized by the selective loss of motor neuron function leading to muscle atrophy and weakness. After symptoms onset patients last 4 to 5 years and ultimately die due to bulbar failure. Animal models have been developed to study ...