Aim: The development of novel silk/nano-sized calcium phosphate (silk/nano-CaP) scaffolds with highly dispersed CaP nanoparticles in the silk fibroin (SF) matrix for bone tissue engineering. Materials & methods: Nano-CaP was incorporated in a concentrated aqueous SF solution (16 wt.%) by using an in situ synthesis method. The silk/nano-CaP scaffolds were then prepared through a combination of salt-leaching/ lyo...
In this study, we investigated the use of short sisal fibre with and without polyethylene-graft-maleic anhydride (PE-g-MA) as a strategy to reinforce cork–polymer composite (CPC) materials. The use of alkali treatment of sisal to improve fibre–matrix adhesion was evaluated. High density polyethylene (HDPE) was used as matrix and the composites were produced in a two-step process using twin-screw extruder follow...
Tese de doutoramento em Engenharia de Materiais ; Advances on forest-based composites, shows a growing trend in the use of lignocellulosic materials as filler and/or reinforcement in plastic composites. Cork-Polymer Composites (CPC) is one of the most promising fields in cork technology to produce new materials based on sustainable development. Cork combined with polymer matrices, has the prospective of lead t...
Composites from high density polyethylene filled with cork powder and coconut short fibres, in two different ratios, were prepared in a twin-screw extruder followed by compression moulding process. The main motivation of this work was to improve the mechanical performance without compromising the use of high weight percentage of natural component used in the preparation of cork-based composites. The morphology ...
This work proposes biodegradable textile-based structures for tissue engineering applications. We describe the use of two polymers, polybutylene succinate (PBS) proposed as a viable multifilamentand silk fibroin (SF), to produce fibre-based finely tuned porous architectures by weft knitting. PBS is here proposed as a viable extruded multifilament fibre to be processed by a textile-based technology. A comparativ...
Macro/micro porous silk scaffolds with nano-sized calcium phosphate (CaP) particles were developed for bone tissue engineering. Different amounts of nano-sized CaP particles 4, 8, 16 and 25% (CaP:silk fibroin, wt/wt) were generated into the highly concentrated aqueous silk fibroin solutions via an in-situ approach. Afterwards, the pure silk and silk/nano-CaP porous scaffolds were produced by a combination of sa...
This study used a rat subcutaneous implantation model to investigate gradual in situ pore formation in a self-regulating degradable chitosan-based material, which comprises lysozyme incorporated into biomimetic calcium phosphate (CaP) coatings at the surface to control the scaffold degradation and subsequent pore formation. Specifically, the in vivo degradation of the scaffolds, the in situ pore formation, and ...
The work creates a viable and profitable alternative to storage or burn of cork powder. ► Cork–polymer composite materials for building applications such as core in flooring. ► The cork composites show low water absorption and low thickness swelling variation. ► Cork improved the fire resistance of the thermoplastic composites. ► Composites with good acoustic behaviour as compare with the commercial fibre board...
New functionalized composite structures were prepared using low-density polyethylene (LDPE), cork powder and different suberins extracted from cork and birch outer bark as coupling agents to promote interfacial adhesion. The compounding was performed under reactive extrusion and samples processed by compression moulding. The morphology of the functionalized composites showed good adhesion between cork and the p...
Early identification of patients who need hospitalization or patients who should be discharged would be helpful for the management of acute asthma in the emergency room. The objective of the present study was to examine the clinical and pulmonary functional measures used during the first hour of assessment of acute asthma in the emergency room in order to predict the outcome. We evaluated 88 patients. The inclu...
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