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The ubiquitin-proteasome pathway, oxidative stress and age-related macular dege...

Age-related macular degeneration (AMD) is the leading cause of blindness in the western world in the population over 60 years of age and its prevalence is likely to rise as a consequence of increasing longevity. While the cause of AMD is currently not known, it has been suggested that multiple factors are involved including environmental, nutritional and genetic factors. Most of these risk factors appear to hav...