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Effect of chaetomellic acid on hematocrit, urine specific gravity and urinary v...

Nogueira, António José M.; Faustino-Rocha, Ana; Teixeira-Guedes, Catarina; Teixeira, Joana; Oliveira, Paula; Colaço, Bruno; Pires, Maria

Chaetomellic acid (CA) is a potent and highly specific inhibitor of ras farnesyl-protein transferase that seems to reduce both functional and histological damage in uninephrectomized rats subjected to renal ischaemia-reperfusion injury. The aim of this work was to evaluate the effect of chronic treatment with CA on hematocrit, urine specific gravity and urinary volume in a model of renal mass reduction. Male Wi...

Data: 2012   |   Origem: Biblioteca Digital do IPB

Effect of chaetomellic acid on hematocrit, urine specific gravity and urinary v...

Nogueira, António José M.; Faustino-Rocha, Ana; Teixeira-Guedes, Catarina; Teixeira, Joana; Oliveira, Paula; Colaço, Bruno; Pires, Maria

Chaetomellic acid (CA) is a potent and highly specific inhibitor of ras farnesyl-protein transferase that seems to reduce both functional and histological damage in uninephrectomized rats subjected to renal ischaemia-reperfusion injury. The aim of this work was to evaluate the effect of chronic treatment with CA on hematocrit, urine specific gravity and urinary volume in a model of renal mass reduction. Male Wi...

Data: 2012   |   Origem: Biblioteca Digital do IPB

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