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Hepcidin serum levels and resistance to recombinant human erythropoietin therap...
Costa, Elísio; Swinkels, Dorine W.; Laarakkers, Coby M.; Rocha-Pereira, Petronila; Rocha, Susana; Reis, Flávio; Teixeira, Frederico; Miranda, VascoThis title was also presented orally at Clinical Biochemistry workshop,Faro, 29 Janeiro, 2010
Neutrophil activation and resistance to recombinant human erythropoietin therap...
Costa, Elísio; Rocha, Susana; Rocha-Pereira, Petronila; Nascimento, Henrique; Castro, Elisabeth; Miranda, Vasco; Faria, Maria do SameiroThe aim of this work was to evaluate the neutrophil activation state in chronic kidney disease (CKD) patients under hemodialysis, and its linkage with resistance to recombinant human erythropoietin (rhEPO) therapy. Methods: We studied 63 CKD patients under hemodialysis and rhEPO treatment (32 responders and 31 non-responders to rhEPO therapy). In 20 of the CKD patients (10 responders and 10 non-responders to rh...
DMT1 (NRAMP2/DCT1) genetic variability and resistance to recombinant human eryt...
Costa, Elísio; Rocha, Susana; Rocha-Pereira, Petronila; Reis, Flávio; Castro, Elisabeth; Teixeira, Frederico; Miranda, Vasco; Faria, Maria do Sameiro
Band 3 profile as a marker of erythrocyte changes in chronic kidney disease pat...
Costa, Elísio; Rocha, Susana; Rocha-Pereira, Petronila; Castro, Elisabeth; Miranda, Vasco; Faria, Maria do Sameiro; Loureio, AlfredoOur aim was to study changes in red blood cell (RBC) membrane band 3 profile, as a cumulative marker of RBC changes, in chronic kidney disease (CKD) patients under haemodialysis and recombinant human erythropoietin (rhEPO) therapy and its linkage with resistance to this therapy. We studied 63 CKD patients, 32 responders and 31 non-responders to rhEPO therapy, and 26 healthy individuals. We evaluated the band 3 ...
Changes in red blood cells membrane protein composition during hemodialysis pro...
Costa, Elísio; Rocha, Susana; Rocha-Pereira, Petronila; Castro, Elisabeth; Miranda, Vasco; Faria, Maria do Sameiro; Loureio, AlfredoOur aim was to evaluate the influence of the hemodialysis (HD) procedure in red blood cells (RBC) membrane protein composition. We evaluated hematological data (RBC count, hemoglobin concentration, and hematimetric indices) and RBC membrane protein composition (linear and exponential gradient polyacrylamide gel electrophoresis in the presence of sodium dodecylsulfate [SDS-PAGE] followed by densitometry analysis...
Cross-talk between inflammation, coagulation/fibrinolysis and vascular access i...
Costa, Elísio; Rocha, Susana; Rocha-Pereira, Petronila; Castro, E.; Reis, Flávio; Teixeira, Frederico; Miranda, Vasco; Faria, Maria do SameiroThis work aimed to study the association between fibrinolytic/endothelial cell function and inflammatory markers in chronic kidney disease (CKD) patients undergoing hemodialysis (HD) and recombinant human erythropoietin (rhEPO) therapies, and its relationship with the type of vascular access (VA) used for the HD procedure. As fibrinolytic/endothelial cell function markers we evaluated plasminogen activator inhi...
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