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P-Cadherin as Prognostic Factor for Loco-Regional Relapse in Breast Cancer
Faria, Gil; Cardoso, Maria João; Martins, Diana; Bettencourt, Herberto; Amendoeira, Isabel; Schimitt, FernandoBackground: Breast cancer is the most frequent malignant tumor and the leading cause of cancer death in women in Portugal. Due to its relation to an increase in distant metastasis and subsequent death, loco-regional relapse is one major concern in breast cancer women. Several classic prognostic factors as tumour size, nodal stage, histological grade, HER2 status and hormonal receptors have been identified as th...
Lynch Syndrome without mutation of Mismatch Repair Genes: The other face of the...
Faria, Gil; Hospital de São João, EPE; Serviço de Cirurgia Geral Faculdade de Medicina da Universidade do Porto, PortugalBackground: Lynch Syndrome (LS) is the most frequent form of hereditary colorectal cancer (CRC) and derives from germinative mutations in the mismatch repais genes (MMR). The clinical diagnosis is based on Amsterdam criteria (AC) but definitive diagnostic is based on the identification of a MMR gene mutation. Of these, MLH1 and MSH2 are the most frequent, followed by MSH6 and rarely by other genes (PMS1 and PMS...
Factores moleculares de prognóstico na recidiva loco-regional do cancro da mama
Faria, Gil Filipe RamadaMestrado em Medicina e Oncologia Molecular ; Master Degree Course in Molecular and Oncology Medicine
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