A ingestão acidental de produtos cáusticos pelas crianças continua a ser um problema actual. Com o objectivo de conhecer a panorâmica dos últimos 8 anos, no Hospital Geral de Santo António (HGSA), os autores fizeram a revisão dos processos clínicos referentes às 88 crianças que deram entrada no Serviço de Urgência deste hospital, de Janeiro de 1988 a Dezembro de 1995, por ingestão de cáusticos e que motivou a r...
Background: Atherosclerotic lesions commonly develop at arterial branch sites. Noninvasive carotid artery ultrasound is a well-established and effective method which allows real-time images and measurements of flow velocities. We aimed to develop a methodology for patient-specific computational 3D reconstruction and blood flow simulation based on ultrasound image data. Material and Methods: Subject-specific stu...
The pyrimidinones mhcpe, 2-methyl-3H-5-hydroxy-6-carboxy-4-pyrimidinone ethyl ester (mhcpe, 1), 2,3- dimethyl-5-benzyloxy-6-carboxy-4-pyrimidinone ethyl ester (dbcpe, 2) and N-methyl-2,3-dimethyl-5- hydroxy-6-carboxyamido-4-pyrimidinone (N-MeHOPY, 3), are synthesized and their structures determined by single crystal X-ray diffraction. The acid–base properties of 1 are studied by potentiometric and spectrophotom...
The Luiz Bandeira Bridge is located along the Portuguese national road EN333-3, breaching the valley of the Vouga River, just northeast of the small village Sejães, in the district of Oliveira de Frades. It is considered to be the oldest concrete bridge in use in Portugal, and one of the oldest in Europe. Since this bridge is at risk of disappearing due to a construction of a dam, the Department of Civil Engine...
Wound management represents a major clinical challenge on what concerns healing enhancement and pain control. The selection of an appropriate dressing plays an important role in both recovery and esthetic ap- pearance of the regenerated tissue. Despite the wide range of available dressings, the progress in the wound care market relies on the increasing interest in using natural-based biomedical products. Herein...
Introdução: Apesar do reconhecimento da sua elevada prevalência e seu adverso impacto clínico, a desnutrição permanece subvalori- zada no contexto hospitalar e agrava-se frequentemente no decurso do internamento. Objectivos: Caracterizar a progressão do estado nutricional e da composição corporal no período pós-operatório imediato de cirurgia electiva major e correlacioná-la com a evolução clínica. Material e m...
Introdução: Diversos estudos sugerem que a citrulinémia pode constituir um parâmetro objectivo e reprodutível da massa enterocitária funcionante. Objectivos: Analisar o valor da citrulinémia na avaliação da função intestinal na síndroma do intestino curto. Material e métodos: Realizou-se um estudo caso-controlo, incluindo 11 doentes com síndroma do intestino curto, resultante de enterectomia extensa e 11 indiví...
An alternative mechanism for the 1,4-assymmetric induction in the stereoselective addition of (R)-pantolactone to 2-phenylpropylketene was theoretically investigated. A mechanism involving an intermolecular proton transfer assisted by two amine molecules was proposed, which considered the active participation of the dimethylethylamine and its ion as proton transfer agents. In the first step, a neutral dimethyle...
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