A Diabetes Insípida é uma das causas pouco habituais de febre de etiologia indeterminada. Descrevemos o caso de urna lactente internado aos novemeses de idade com febre, má progressão ponderal e atraso no desenvolvimento motor. As causas habituais destas situações foram excluídas por examesexaustivos. Alguns meses mais tarde constatámos o aparecimento de poliúria e polidipsia. A prova com desmopressina fez o di...
A Qualidade de Vida Relacionada com a Saúde (QVRS) tem sido estudada na Doença Pulmonar Obstrutiva Crónica (DPOC). Avaliou-se a QVRS em 20 pacientes com DPOC e correlacionou-se o St George’s Respiratory Questionnaire (SGRQ) e o The Medical Outcomes Study Short Form 36 (SF-36) através do Coeficiente de Correlação de Pearson, cujo nível de significância estatística foi de 0,01. Aplicou-se o SGRQ, SF-36, Escala de...
The oxidative behavior of viloxazine was studied at a glassy carbon electrode in different buffer systems using cyclic, differential pulse and square-wave voltammetry. The oxidation process was shown to be diffusion-controlled and irreversible over the studied pH. The voltammetric study of the model compounds, 2-ethoxyanisole and morpholine, associated with quantum mechanical (DFT) calculations, allowed to eluc...
Trihydroxycinnamic derivatives were synthesized and evaluated for their antioxidant and cytotoxic activities. The ester derivatives exhibited a higher radical-scavenging activity, when liposomes were used as target systems, a fact which may be related to their lipophilicity and conformational preferences. These compounds were found to display significant growth inhibition and cytotoxic effects towards a human c...
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