Encontrados 6 documentos, a visualizar página 1 de 1
Poly(N-Isopropylacrylamide) surface-grafted ghitosan membranes as a new substra...
Silva, Ricardo M. P. da; López Pérez, Paula M.; Elvira, C.; Mano, J. F.; San Román, J.; Reis, R. L.The immobilization of poly(N-isopropylacrylamide) (PNIPAAm) on chitosanmembranes was performed in order to render membranes with thermo-responsive surface properties. The aim was to create membranes suitable for cell culture and in which confluent cell sheets can be recovered by simply lowering the temperature. The chitosan membranes were immersed in a solution of the monomer that was polymerized via radical in...
Influence of β-radiation sterilization in properties of new chitosan/soybean pr...
Silva, R. M.; Elvira, C.; Mano, J. F.; San Román, J.; Reis, R. L.Novel chitosan (cts) and soybean protein isolate (SI) blended membranes were prepared. These membranes were produced by solvent casting. Besides combining the advantages of both materials, cts/SI membranes exhibit a biphasic structure that will eventually originate in situ porous formation, through a two-step degradation mechanism. In this particular work the effect of -radiation over the properties of these me...
Influence of beta-radiation sterilisation in properties of new chitosan/soybean...
Silva, R. M.; Elvira, C.; Mano, J. F.; Roman, J. San; Reis, R. L.Novel chitosan (cts) and soybean protein isolate (SI) blended membranes were prepared. These membranes were produced by solvent casting. Besides combining the advantages of both materials, cts/SI membranes exhibit a biphasic structure that will eventually originate in situ porous formation, through a two-step degradation mechanism. In this particular work the effect of beta-radiation over the properties of thes...
Plasma and chemical-induced graft polymerization on the surface of starch-based...
Elvira, C.; Feng, Y.; Azevedo, M. C.; Rebouta, L.; Cunha, A. M.; San Román, J.; Reis, R. L.Plasma and chemical induced graft polymerization of acrylic monomers on starch-based biomaterials has been performed with the aim to improve cell adhesion and proliferation on the surface of the polymers, in order to adequate their properties for bone tissue engineering scaffolding applications. Plasma and chemical surface activation was aimed to induce the polymerization of acrylic polar monomers being carrie...
Porous starch-based drug delivery systems processed by a microwave route
Malafaya, P. B.; Elvira, C.; Gallardo, A.; San Román, J.; Reis, R. L.A new simple processing route to produce starch-based porous materials was developed based on a microwave baking methodology. This innovative processing route was used to obtain non-loaded controls and loaded drug delivery carriers, incorporating a non-steroid anti-inflammatory agent. This bioactive agent was selected as model drug with expectations that the developed methodology might be used for other drugs a...
Surface modification tailors the characteristics of biomimetic coatings nucleat...
Oliveira, A. L.; Elvira, C.; Vásquez, Blanca; San Román, J.; Reis, R. L.This work describes the influence of surface pretreatments over the nucleation and growth of an apatite layer, formed by a biomimetic process, on which a bioactive glass is used as a precursor of the calcium-phosphate (Ca-P) formation on the materials surface. SEVA-C, a corn starch-based biodegradable blend, was used as substrate. The surfaces were pretreated during various periods by: (i) physical methods, nam...
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