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Microangiopathic hemolytic anemia. A form of presentation of stomach neoplasm.

Oliveira, A; Serviço de Medicina I, Hospital de Santa Maria, Lisboa.; Frazão, A; Duarte, P C; Nogueira, B

The authors report the case of a 53-year-old female with symptomatic anemia and hemorrhagic diathesis. The patient presented thrombocytopenia, microangiopathic hemolytic anemia and leukoerythroblastic reaction in peripheral blood film. The diagnosis of metastatic gastric carcinoma was made by subsequent studies. A review is made of the literature concerning microangiopathic hemolytic anemia, namely its etiology...

Data: 1970   |   Origem: Acta Médica Portuguesa

The cardiac toxicity of cancer chemotherapy.

Sequeira, J F; Serviço de Medicina I, Hospital de Santa Maria, Lisboa.; Madruga, I M; Ribeiro, M; Duarte, P C; Ferreira, D C; Sarmento, J L

The presence of secondary effects following the administration of chemotherapeutic drugs is an important limitation to cancer therapy. Of these, cardiotoxicity is of crucial importance due to its negative influence on survival. The anthracyclines and cyclophosphamide are the most important cardiotoxic antineoplastic agents currently used. If we agree on a ceiling dosage of chemotherapy we will deprive some pati...

Data: 1970   |   Origem: Acta Médica Portuguesa

Essential thrombocythemia. Apropos a case of cerebrovascular stroke.

Oliveira, A S; Serviço de Medicina I, Hospital Universitário de Santa Maria, Lisboa.; Miranda, M P; Duarte, P C; Sarmento, J N

The authors report the case of a 60-year-old white man with a previous history of pulmonary tuberculosis, smoking habits, hypertension, intermittent claudication and erythromelalgia, admitted to our ward with an ischemic cerebral event. Initial laboratory evaluation documented thrombocytosis (platelet-950000/mm3) and discrete anemia. Additional studies confirmed the diagnosis of essential thrombocythemia, meeti...

Data: 1970   |   Origem: Acta Médica Portuguesa

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