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Information and Communication Technologies in Long-term and Palliative Care
Reis, Andreia; Araújo Pedrosa, Anabela; Dourado, Marília; Reis, CatarinaIn the beginning of the 21st century we experienced a paradigm shift between the acute and infectious diseases to the chronic conditions, sustained by the aging of the population. Nevertheless, the education system for health professionals kept the traditional educational models. The main idea of the work here presented is to provide a literature review of the state of the art of information and communicatio...
CD26/DPPIV expression and 8-azaguanine response in T-acute lymphoblastic leukae...
Dourado, Marília; Sarmento, Ana Bela; Pereira, Sofia Vale; Alves, Vera; Silva, Teresa; Pinto, Anabela Mota; Rosa, Manuel SantosDipeptidyl peptidase IV, a cell membrane surface protease also known as CD26 (CD26/DPPIV), is known to play multiple functions in human organism, where it is largely expressed, for instance, in the development of human cancer and metastasis as well as in chemotherapy response. ; http://www.sciencedirect.com/science/article/B6TBB-4M57H33-1/1/0f52b91095cb3dd6eac759bb2b90d060
CD26/DPPIV expression and 8-azaguanine response in T-acute lymphoblastic leukae...
Dourado, Marília; Sarmento-Ribeiro, Ana Bela; Vale-Pereira, Sofia; Alves, Vera; Silva, Teresa; Mota-Pinto, Anabela; Santos-Rosa, ManuelDipeptidyl peptidase IV, a cell membrane surface protease also known as CD26 (CD26/DPPIV), is known to play multiple functions in human organism, where it is largely expressed, for instance, in the development of human cancer and metastasis as well as in chemotherapy response. The objective of this work was to study the CD26 membrane expression and DPPIV activity in T-acute leukaemia cell lines (CEM and MOLT3) ...
Substância P na asma brônquica - Intervenção nos mecanismos de oxidação e activ...
Todo-Bom, Ana; Mota-Pinto, Anabela; Vale-Pereira, Sofia; Alves, Vera; Dourado, Marília; Chieira, Celso; Santos-Rosa, ManuelA Substância P (SP) descrita pela primeira vez no início do século XX, desempenha uma acção relevante a nível da inflamação neuroimune e do tónus da musculatura lisa. A asma brônquica é uma patologia crónica, com prevalência crescente em todos os países desenvolvidos. A inflamação crónica subjacente à doença pode limitar a reversibilidade funcional do órgão (respiratório), particularmente em casos clínicos mais...
CD26/DPPIV and response to hepatitis B vaccination
Dourado, Marília; Alves, Vera; Mesquita, Luis; Ramos, Isabel; Mota-Pinto, Anabela; Santos-Rosa, ManuelThe prevention of hepatitis B is important, since it is responsible for significant morbidity and mortality around the world. Unfortunately, hepatitis B vaccine does not always induce protective immunity. The lack of immune response to vaccine (non-responders) can depend on individual characteristics. The objective of this study was to correlate the CD26/DPPIV cellular expression and DPPIV serum activity with H...
Substance P in Long-Lasting Asthma. Immunoinflammatory pathways
Todo-Bom, Ana; Mota-Pinto, Anabela; Vale-Pereira, Sofia; Alves, Vera; Dourado, Marília; Santos-Rosa, ManuelBackground: Substance P (SP) was described at the beginning of the 20th Century, and its biological action was recognized to have implications in neurogenic inflammation and constriction of smooth muscles. The changes associated with inflammatory chronicity can compromise organ function reversibility. The role of neuromechanisms in the pathology of the disease has been investigated in order to achieve better di...
Doseamento das granzimas A e B na sarcoidose pulmonar (estudo experimental)
Dourado, Marília; Bento, Joana; Mesquita, Luis; Marques, Alcide; Vale-Pereira, Sofia; Sarmento-Ribeiro, Ana Bela; Mota-Pinto, AnabelaSarcoidosis is a systemic disease of unknown aetiology, morphologically characterized by well-formed epithelioid granulomas, which show little or no central necrosis. These may be present in any organ or tissue. The lung is the most frequently and prominently involved target. The granuloma is often very sharply demarcated from the adjacent tissue and is surrounded by a mantle of lymphocytes, which mediate lysis...
CD26/DPPIV and response to hepatitis B vaccination
Dourado, Marília; Alves, Vera; Mesquita, Luis; Ramos, Isabel; Pinto, Anabela Mota; Rosa, Manuel SantosThe prevention of hepatitis B is important, since it is responsible for significant morbidity and mortality around the world. Unfortunately, hepatitis B vaccine does not always induce protective immunity. The lack of immune response to vaccine (non-responders) can depend on individual characteristics. ; http://www.sciencedirect.com/science/article/B6TBB-4DBT0M2-1/1/263a1829afdc0987487d1075febcb5e9
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