The androgens testosterone (T) and dihydrotestosterone (DHT), besides playing an important role in prostate development and growth, are also responsible for the development and progression of benign prostate hyperplasia (BPH) and prostate cancer. Therefore, the actions of these hormones can be antagonized by preventing the irreversible conversion of T into DHT by inhibiting 5a-reductase (5a-R). This has been a ...
Objectives: African histoplasmosis caused by the fungus Histoplasma capsulatum var. duboisii, is a rare endemic mycosis occuring in western and central regions of sub-Saharian Africa. For unknown reasons, although HIV infection and H. capsulatum var. duboisii coexist in Africa, this coinfection remains rare. In Europe, diagnosed cases of African histoplasmosis are all imported. We describe a case of African his...
A larva migrans cutânea representa uma das dermatoses mais frequentes nos turistas que regressam de países tropicais e sub-tropicais. O agente mais frequente é a larva Ancylostoma brasiliensis que habita no intestino de cães e gatos. Os humanos são afetados quando contatam com solo contaminado com os excrementos de animais infetados. Apresentamos o caso de uma professora, 39 anos de idade, natural e residente e...
Peroxiredoxins (Prxs) play major roles in preventing oxidative damage and their function is consistent with the presence of Prx isoforms in most, if not all, cellular compartments and their expression is dependent on environmental conditions. The aim of this study was to identify and characterize genes encoding Prxs in Vitis vinifera. Quantitative real time polymerase chain reaction (qRT PCR) was used to determ...
; Apresenta-se o projecto dum controlador, que implementa a interface do μP68030 a uma memória dinâmica. A memória permite o acesso de bytes, words e longwords, suportando ainda um modo de acesso rápido (‘Nibble’). Para aumentar a confiabilidade (‘reliability’), a interface inclui ainda um circuito de detecção e corre...
Acoustic insulation is an important requirement for the human life today, since noise affects the efficiency of day-to-day activities and even cause various health problems Materials based on fibrous structures show very good acoustic insulation properties, which however strongly depends on the type of structures used. The present paper reports the qualitative analysis of the acoustic insulation behavior of var...
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