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Antitumor activity of hierridin B, a cyanobacterial secondary metabolite found ...
Leão, Pedro N.; Costa, Margarida; Ramos, Vitor; Pereira, Alban R.; Fernandes, Virginia C.; Domingues, Valentina F.; Gerwick, William H.Cyanobacteria are widely recognized as a valuable source of bioactive metabolites. The majority of such compounds have been isolated from so-called complex cyanobacteria, such as filamentous or colonial forms, which usually display a larger number of biosynthetic gene clusters in their genomes, when compared to free-living unicellular forms. Nevertheless, picocyanobacteria are also known to have potential to pr...
Antitumor activity of hierridin B, a cyanobacterial secondary metabolite found ...
Leão, Pedro N.; Costa, Margarida; Ramos, Vitor; Pereira, Alban R.; Fernandes, Virgínia C.; Domingues, Valentina F.; Gerwick, William H.Cyanobacteria are widely recognized as a valuable source of bioactive metabolites. The majority of such compounds have been isolated from so-called complex cyanobacteria, such as filamentous or colonial forms, which usually display a larger number of biosynthetic gene clusters in their genomes, when compared to free-living unicellular forms. Nevertheless, picocyanobacteria are also known to have potential to pr...
Bisphenol A migration from plastic materials: direct insight of ecotoxicity in ...
Mansilha, Catarina; Silva, Poliana; Rocha, Sónia; Gameiro, P.; Domingues, Valentina F.; Pinho, Carina; Ferreira, Isabel M. P. L. V. O.Bisphenol A (BPA) is an endocrine disrupting chemical (EDC) whose migration from food packaging is recognized worldwide. However, the real overall food contamination and related consequences are yet largely unknown. Among humans, children’s exposure to BPA has been emphasized because of the immaturity of their biological systems. The main aim of this study was to assess the reproductive impact of BPA leached fr...
Biocomplementation of SVE to achieve clean-up goals in soils contaminated with ...
Soares, António Alves; Pinho, Maria Teresa; Albergaria, José Tomás; Domingues, Valentina F.; Alvim-Ferraz, Maria da Conceição M.Soil vapor extraction (SVE) and bioremediation (BR) are two of the most common soil remediation technologies. Their application is widespread; however, both present limitations, namely related to the efficiencies of SVE on organic soils and to the remediation times of some BR processes. This work aimed to study the combination of these two technologies in order to verify the achievement of the legal clean-up go...
Outdoor and indoor benzene evaluation by GC-FID and GC-MS/MS
Sousa, José A.; Domingues, Valentina F.; Rosas, Mónica S.; Ribeiro, Susana; Alvim-Ferraz, Maria da Conceição M.The evaluation of benzene in different environments such as indoor (with and without tobacco smoke), a city area, countryside, gas stations and near exhaust pipes from cars running on different types of fuels was performed. The samples were analyzed using gas chromatography (GC) with flame ionization detection (FID) and tandem mass spectrometric detection (MS/MS) (to confirm the identification of benzene in the...
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