Encontrados 5 documentos, a visualizar página 1 de 1
Translocating the blood-brain barrier using electrostatics
Ribeiro, Marta M. B.; Domingues, Marco M.; Freire, João M.; Santos, Nuno C.; Castanho, Miguel A. R. B.Copyright © 2012 Ribeiro,Domingues, Freire,Santos and Castanho. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc. ; Mammalian cell membranes regulate homeostas...
Using zeta-potential measurements to quantify peptide partition to lipid membranes
Freire, João M.; Domingues, Marco M.; Matos, Joana; Melo, Manuel N.; Veiga, Ana Salomé; Santos, Nuno C.; Castanho, Miguel A. R. B.© The Author(s) 2011. This article is published with open access at Springerlink.com. ; Open Access: This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. ; Many cellular phenomena occur on the biomembranes. There are plenty...
Quantifying molecular partition of charged molecules by Zeta-potential measurem...
Freire, João Miguel; Domingues, Marco M.; Matos, Joana; Melo, Manuel N.; Veiga, Ana Salomé; Santos, Nuno C.; Castanho, Miguel A. R. B.Copyright ©2010 The European Peptide Society
Laser-light scattering approach to peptide–membrane interaction
Domingues, Marco M.; Santos, Nuno C.© International University Line, 2010 ; Membrane-active peptides are becoming widely used, mainly due to their high therapeutic potential. Although the therapeutic action is characterized, the mechanisms of interaction are often unclear or controversial. In biophysical studies, non-invasive techniques are overlooked when studying the effect of peptides on membranes. Light scattering techniques, such as dynamic...
Fold-unfold transitions in the selectivity and mechanism of action of the N-ter...
Domingues, Marco M.; Lopes, Sílvia C. D. N.; Santos, Nuno C.; Quintas, Alexandre; Castanho, Miguel A. R. B.© 2009 by the Biophysical Society ; Septic or endotoxic shock is a common cause of death in hospital intensive care units. In the last decade numerous antimicrobial peptides and proteins have been tested in the search for an efficient drug to treat this lethal disease. Now in phase III clinical trials, rBPI21, a recombinant N-terminal fragment of the bactericidal/permeability-increasing protein (BPI), is a pro...
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