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Simultaneous characterization and quantification of phenolic compounds in Thymu...

Thymus x citriodorus is a Lamiaceae plant extensively cultivated in Mediterranean region and used for centuries in culinary and in traditional medicine. The present work describes the detailed phenolic composition of T. x citriodorus for the first time, the by means of HPLC-DAD, ESI-MS and MSn and nuclear magnetic resonance (NMR) analyses. The ethanolic extract of T. x citriodorus was analyzed by reversed phase...

Characterization by electrospray ionization and tandem mass spectrometry of rha...

In this work, biosurfactants produced by two Pseudomonas aeruginosa strains isolated from Brazilian crude oils were identified by proton nuclear magnetic resonance ((1)H NMR) and further characterized by mass spectrometry (MS) coupled with electrospray ionization (ESI) and tandem mass spectrometry (MS/MS) analysis in positive mode and their surface activities evaluated. Mono-rhamnolipids and di-rhamnolipids wer...

Lipidomic approach of the biological activity of tacrine and two tacrine-analog...

Tacrine and its analogues impair mitochondrial function and bioenergetics : a l...

Tacrine is an acetylcholinesterase inhibitor used as cognitive enhancer in Alzheimer's disease treatment. However, the low therapeutic efficiency and the high incidence of side effects have limited its clinical use. In the present study, the molecular mechanisms underlying the brain activity of tacrine and two novel tacrine analogues (T1, T2) were approached focusing on three aspects: i) effects on brain cholin...

Phenolic constituents of lamium album: focus on isoscutellarein derivatives

Lamium album L. is an edible plant which is consumed raw or cooked, in particular in the Mediterranean and surrounding areas. It is also consumed as tea infusions and as a main component of food supplements, because of its pharmacological effects. Despite being consumed by humans for centuries, the chemical composition of L album L is far from being understood. In this study, a purified ethanolic extract (PEEL)...

Cytisus multiflorus: source of antioxidant polyphenols

The present study investigates the phenolic composition and the antioxidant capacity of an ethanolic extract from flowers of C. multiflorus. As determined by HPLC-DAD, ESI-MSn and NMR combined analysis, this extract was mainly composed of chrysin-7-O-β-D-glycopyranoside, and also contained considerable amounts of rutin, a dihydroxyflavone isomer of chrysin and glycosidic derivatives of luteolin and apigenin. Th...

Cytisus multiflorus: source of antioxidant polyphenols

The present study investigates the phenolic composition and the antioxidant capacity of an ethanolic extract from flowers of C. multiflorus. As determined by HPLC-DAD, ESI-MSn and NMR combined analysis, this extract was mainly composed of chrysin-7-O-β-D-glycopyranoside, and also contained considerable amounts of rutin, a dihydroxyflavone isomer of chrysin and glycosidic derivatives of luteolin and apigenin. Th...

Novel flavones in Lamium L. genus

The main aim of this work is to determine the phenolic composition of a Lamium album L. purified extract, in order to contribute for the chemical characterization of this plant. Moreover, it also intends to emphasize its antioxidant properties. As established by HPLC-DAD and ESI-MSn combined analysis, verbascoside was the major phenolic constituent of Lamium album L. purified extract, as previously described by...

Cytisus multiflorus: source of antioxidant polyphenols

The present study investigates the phenolic composition and the antioxidant capacity of an ethanolic extract from flowers of C. multiflorus. As determined by HPLC-DAD, ESI-MSn and NMR combined analysis, this extract was mainly composed of chrysin-7-O-β-D-glycopyranoside, and also contained considerable amounts of rutin, a dihydroxyflavone isomer of chrysin and glycosidic derivatives of luteolin and apigenin. Th...

Novel flavones in Lamium L. genus

The main aim of this work is to determine the phenolic composition of a Lamium album L. purified extract, in order to contribute for the chemical characterization of this plant. Moreover, it also intends to emphasize its antioxidant properties. As established by HPLC-DAD and ESI-MSn combined analysis, verbascoside was the major phenolic constituent of Lamium album L. purified extract, as previously described by...