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Activity of Thymus capitellatus volatile extract, 1,8-cineoleand borneol agains...
Machado, M.; Dinis, A. M.; Santos-Rosa, M.; Alves, V.; Salgueiro, L.; Cavaleiro, C.; Sousa, M. C.In the search for new leishmanicidal agents, Thymus capitellatus Hoffmanns. & Link (familyLamiaceae) volatile extract and its major compounds, 1,8-cineole and borneol, were testedagainst Leishmania infantum, Leishmania tropica and Leishmania major. Plant volatile extract(essential oil) was analysed by GC and GC–MS and the activity of essential oil on Leishmaniapromastigotes viability was assessed using tetrazol...
Activity of Thymus capitellatus volatile extract, 1,8-cineole and borneol again...
Machado, M.; Dinis, A. M.; Santos-Rosa, M.; Alves, V.; Salgueiro, L.; Cavaleiro, C.; Sousa, M. C.In the search for new leishmanicidal agents, Thymus capitellatus Hoffmanns. & Link (family Lamiaceae) volatile extract and its major compounds, 1,8-cineole and borneol, were tested against Leishmania infantum, Leishmania tropica and Leishmania major. Plant volatile extract (essential oil) was analysed by GC and GC–MS and the activity of essential oil on Leishmania promastigotes viability was assessed using tetr...
Studies on the toxicity of an aqueous suspension of C60 nanoparticles using a b...
Santos, Sandra M. A.; Dinis, A. M.; Rodrigues, David M. F.; Peixoto, Francisco; Videira, Romeu A.; Jurado, A.S.The increasing use of C60 nanoparticles and the diversity of their applications in industry and medicine has led to their production in a large scale. C60 release into wastewaters and the possible accumulation in the environment has raised concerns about their ecotoxicological impact. In the present study, an aqueous suspension of C60 nanoparticles was prepared and its potential toxicity studied in laboratory, ...
A arte atlântica do Crastoeiro (Norte de Portugal) : contextos e significados
Dinis, A. Pereira; Bettencourt, Ana M. S.Basados en los resultados de las excavaciones arqueológicas realizadas en los complejos I y II del arte atlántico de Crastoeiro, localizados en el Monte de la Senhora da Graça y partiendo del supuesto de que los individuos no sólo viven en un espacio sino que también están inmersos o incorporados en el, este trabajo tiene como objetivo establecer algunas interpretaciones no sólo sobre la biografía de cada uno d...
Levels of ochratoxin A in serum from urban and rural Portuguese populations and...
Lino, C. M.; Baeta, M. L.; Henri, M.; Dinis, A. M. P.; Pena, A. S.; Silveira, M. I. N.Urban and rural population exposure to ochratoxin A (OTA) in central zone of Portugal was investigated in three places: Coimbra, Verride and Ereira. ; http://www.sciencedirect.com/science/article/B6T6P-4PYYTY1-6/1/d92ebdd35d9b9545c0b4cc338410924b
O sopro num coração normal
Martins, P; Dinis, A; Canha, J; Ramalheira, G; Castela, EInnocent heart murmur is a frequent auscultatory finding in children. The diagnosis is essentially clinical, without need for further investigation. However, excluding heart disease can be a difficult task. This review article describes some features of medical history and physical examination that help in this differentiation. The role of diagnostic tests is also examined.
Dual Effect of Nitrate Therapy for Cyclosporine-Induced Hypertension on Vascula...
Reis, F.; Lemos, E. Teixeira de; Almeida, L.; Parada, B.; Garrido, A. P.; Rocha-Pereira, P.; Santos-Silva, A.; Santos-Dias, J.; Dinis, A.The present study sought to evaluate the prevention and reversion effects of isosorbide-5-mononitrate (Is-5-Mn) on the development of hypertension (HT) and on the underlying vascular and platelet morphofunctional disturbances, using an animal model of cyclosporine (CsA)-induced HT. The following rat groups (n = 8) were tested: (1) a control group (orange juice, for 7 weeks); (2) the CsA group (5 mg/kg/d for 7 w...
Ochratoxin A in nephropathic patients from two cities of central zone in Portugal
Dinis, A. M. P.; Lino, C. M.; Pena, A. S.Ochratoxin A (OTA) produced by Aspergillus and Penicilliumgenera contaminates several foods. OTA is nephrotoxic to all animal species studied so far, and most likely to humans, who show the longest half-life for elimination of this toxin among all examined species. OTA has other toxic effects such as teratogenicity, immunotoxiity, genotoxicity, and is also mutagenic and carcinogenic, all of which lead to life-t...
A contribution to the ultrastructural knowledge of the pollen exine in subtribe...
Pereira Coutinho, A.; Dinis, A. M.Abstract To better understand the relationships within the Asteroideae and Inuleae, the structure of the pollen exine was investigated in seven genera and nine species of the subtribe Inulinae using LM, TEM and SEM. All taxa have a senecioid pattern of exine. The tectal complex consists of three main layers that differ in thickness and morphology: a tectum, a columellar layer, and a layer consisting of the bas...
Signalling pathways in pollen germination and tube growth
Malhó, R.; Liu, Q.; Monteiro, D.; Rato, C.; Camacho, L.; Dinis, A.Summary. Signalling is an integral component in the establishment and maintenance of cellular identity. In plants, tip-growing cells represent an ideal system to investigate signal transduction mechanisms, and among these, pollen tubes (PTs) are one of the favourite models. Many signalling pathways have been identified during germination and tip growth, namely, Ca2+, calmodulin, phosphoinositides, protein kina...
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