The authors would like to thank Rui Gomes for the help in the application of electrophysio- logical techniques and Luís Martins and Miguel Carneiro for the histological preparations. ; Chronic stress impairs cognitive function, namely on tasks that rely on the integrity of cortico-limbic networks. To unravel the functional impact of progressive stress in cortico-limbic networks we measured neural activity and ...
Exposure to a novel environment triggers the response of several brain areas that regulate emotional behaviors. Here, we studied theta oscillations within the hippocampus (HPC)-amygdala (AMY)-medial prefrontal cortex (mPFC) network in exploration of a novel environment and subsequent familiarization through repeated exposures to that same environment; in addition, we assessed how concomitant stress exposure cou...
A modernização das sociedades contemporâneas atenuou algumas características da desigualdade de género através da entrada da mulher no mercado de trabalho e no acesso a esferas de acção exclusivamente masculinas, mas a maior capacitação social da mulher, e mesmo a sua participação política e em processos decisórios, não deve camuflar a persistência de dinâmicas discriminatórias, em particular quando articuladas...
This paper describes a low-power/low-voltage CMOS wireless interface (CMOS-WiI) at 5.7 GHz with dry electrodes for congnitive networks. The electrodes are 4 x 4 microtip arrays and acquire electroencephalogram (EEG) signals in key- points for processing. The CMOS-WiI was fabricated in a UMC 0.18 µm RF CMOS process and its total power consumption is 23mW with a voltage-supply of only 1.5 V. The carrier frequency...
The risk of developing neurodegenerative diseases increases with age. Although many of the molecular pathways regulating proteotoxic stress and longevity are well characterized, their contribution to disease susceptibility remains unclear. In this study, we describe a new Caenorhabditis elegans model of Machado–Joseph disease pathogenesis. Pan-neuronal expression of mutant ATXN3 leads to a polyQ-length dependen...
Objetivou-se neste estudo avaliar a tensão superficial estática, o pH e a produção da espuma de misturas em tanque de glyphosate + chlorimuron-ethyl, associadas ou não com adjuvantes. Dois trabalhos foram realizados, sendo a primeira etapa desenvolvida em delineamento inteiramente casualizado com seis tratamentos e 20 repetições, representados por soluções dos herbicidas glyphosate (540,0 g e.a. ha-1) e chlorim...
Initially described 40 years ago (Rosai), the undifferentiated osteoclastic-type giant cell carcinoma (IOGCC) is a variant of ductal adenocarcinoma and accounts for less than 1% of exocrine pancreatic tumors. Its extreme rarity, with consequent existence of few reports and clinical experience, leads to the arousal of doubts with regard to its histogenesis, types of approach and therapeutical attitudes. It is im...
The present seismic tomographic study is focused around Algarve region, in South of Portugal. To locate the seismic events and find the local velocity structure of epicentral area, the P and S arrival times at 38 stations are used. The data used in this study were obtained during the Algarve campaign which worked from January/2006 to July/2007. The preliminary estimate of origin times and hypocentral coordinate...
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