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Polymorphism in gidB gene as a genetic marker for the mycobacterium tuberculosi...

Development of streptomycin-resistance in Mycobacterium tuberculosis is usually associated with mutations in rpsL and rrs genes, although up to 50% of clinical streptomycin-resistant isolates may present no mutation in either of these genes. The situation in Lisbon Health Region is similar, although mutations in rrs gene are only rarely detected. In the present report we investigate the role of gidB gene mutati...

Correlation between streptomycin intermediate-level resistance and gidB mutatio...

Development of streptomycin-resistance in Mycobacterium tuberculosis is usually associated with mutations in rpsL and rrs genes, although up to 50% of clinical streptomycin-resistant isolates may present no mutation in either of these genes. The situation in Lisbon Health Region is similar, although mutations in rrs geneare only rarely detected. In the present report we investigate the role of gidB gene mutatio...

Biodegradability enhancement and detoxification of cork processing wastewater m...

Cork boiling wastewater pollutants were fractionated by sequential use of four ultrafiltration membranes and five fractions were obtained: four retentates (>100, 50-100, 20-50 and 10-20 kDa) and one permeate (<10 kDa); which were used to study the correlation of molecular size with biodegradability and toxicity before and after ozonation. The results show that molecular size is correlated with organic load and ...

Evaluation of the ability of C. albicans to form biofilm in the presence of pha...

Pseudomonas aeruginosa and Candida albicans are disparate microbial species, but both are known to be opportunistic pathogens frequently associated with nosocomial infections. The aim of this study was to provide a better understanding of the interactions between these microorganisms in dual-species biofilms. Several bacteriophage-resistant P. aeruginosa phenotypes have been isolated and were used in dual-speci...

Prevalence of Overweight, Obesity, and Abdominal Obesity in a Representative Sa...

This study determined the prevalence of overweight, obesity, and abdominal obesity in the Portuguese adults and examined the relationship between above mentioned prevalences and educational level. Body mass, stature, and waist circumference were measured in a representative sample of the Portuguese population aged 18–103 years (n = 9,447; 18–64 years: n = 6,908; $65 years: n = 2,539). Overweight and obesity cor...

Medo da compaixão : estudo das propriedades psicométricas da Fears of Compassio...

A Compaixão tem sido cada vez mais alvo de interesse, tendo associada a si um vasto conjunto de investigações sobre as suas manifestações, em diversas populações. O treino de competências e atributos compassivos tem revelado um impacto significativo na redução de sintomatologia psicopatológica e na promoção do bem-estar psicológico. Contudo, tem-se verificado em contexto terapêutico que para alguns sujeitos o d...

Psychosocial factors associated with embryo donation for scientific research in...

The ability of C. albicans to form biofilm in the presence of sensitive and pha...

P. aeruginosa and C. albicans are human opportunistic pathogens frequently associated with nosocomial infections. Pathogenic interactions between them have already been identified and it has been reported that C. albicans’ morphology and virulence are significantly affected by the presence of P. aeruginosa. In this work, the interaction between these 2 microorganisms in mixed biofilms was studied. The behavior ...

Tetrahydroquinazoline-substituted chromones from Diels–Alder reaction of (E)-2-...

The Diels-Alder reaction of (E)-2-styrylchromones with a pyrimidine ortho-quinodimethane is reported for the first time. These cycloaddition reactions afford mixtures of two regioisomeric tetrahydroquinazoline-substituted chromones in moderate to excellent global yields. Irrespectively of the substituents on the 2-styrylchromones, the 2-(7-aryl-4-methoxy-2-methyl-5,6,7,8-tetrahydroquinazolin-6-yl)chromone deriv...

Estudo da Contaminação de Águas pela Extração Mineira de Carvão em S. Pedro da ...