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Control of the pinewood nematode Bursaphelenchus xylophilus by essential oils a...
Barbosa, Pedro; Vieira, Paulo; Dias, LS; Pedro, LG; Barroso, JG; Figueiredo, AC; Mota, ManuelThe pinewood nematode (PWN), Bursaphelenchus xylophilus, is a serious threat to forest ecosystems at a global scale. The nematode has become a major quarantine problem due to its capability to completely destroy Pinus spp. trees, with great damage to the wood industry. Controlling the nematode inside a living tree is quite difficult, the techniques used being often ineffective and quite expensive. In the coming...
Nematoxic effect of essential oils and their fractions against the pinewood nem...
Faria, JMS; Barbosa, Pedro; Mota, Manuel; Figueiredo, ACThe pinewood nematode (PWN) Bursaphelenchus xylophilus is a highly pathogenic plant parasite that greatly affects pine forests. In Portugal, the most affected species is Pinus pinaster Aiton. Despite great efforts, since its fist detection in 1999, the PWN has spread through the country, including Madeira Island, having been recently detected in Spain [1,2]. Containing this pest is of the utmost importance for ...
Prognóstico Obstétrico de Pacientes Portadoras de Diabetes Mellitus Pré-Gestaci...
Robalo Fernandes, R; Simões, AF; Figueiredo, AC; Ribeiro, AR; Aleixo, F; Teixeira, S; Guerra Aragüés; Amaral, NOBJETIVO: Avaliar as alterações epidemiológicas, de perfil clínico e de prognóstico obstétrico em pacientes portadoras de diabetes mellitus pré-gestacional. MÉTODOS: Estudo retrospetivo (coorte) de todas as gestações simples, com diagnóstico de diabetes prévio que foram seguidas num centro com apoio perinatal diferenciado entre 2004 e 2011 (n=194). Analisaram-se tendências relacionadas com dados demográficos e ...
Bartholin's Gland Cysts: Management with Carbon-Dioxide Laser Vaporization
Figueiredo, AC; Duarte, P; Gomes, T; Borrego, J; Marques, COBJETIVO: Avaliar a eficácia, a taxa de recorrência e as complicações da vaporização laser com CO2 no tratamento dos cistos da glândula de Bartholin. MÉTODOS: Estudo retrospectivo com 127 pacientes que apresentavam cistos sintomáticos da glândula de Bartholin submetidas à vaporização laser CO2 na nossa instituição de janeiro de 2005 a junho de 2011. Foram excluídas todas as pacientes com abcessos da glândula de...
Phosphonocarboxylates inhibit the second geranylgeranyl addition by Rab geranyl...
Baron, RA.; Tavare, R.; Figueiredo, AC.; Blazewska, KM.; Kashemirov, BA.; McKenna, CE.; Ebetino, FH.; Taylor, A.; Rogers, MJ.; Coxon, FP.; Seabra, MC.Rab geranylgeranyl transferase (RGGT) catalyzes the post-translational geranylgeranyl (GG) modification of (usually) two C-terminal cysteines in Rab GTPases. Here we studied the mechanism of the Rab geranylgeranylation reaction by bisphosphonate analogs in which one phosphonate group is replaced by a carboxylate (phosphonocarboxylate, PC). The phosphonocarboxylates used were 3-PEHPC, which was previously report...
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