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Effect of a selective nonsteroidal anti-inflammatory inhibitor of cyclooxygenas...

Leite,A.Z.A.; Sipahi,A.M.; Damião,A.O.M.C.; Garcez,A.T.; Buchpiguel,C.A.; Lopasso,F.P.; Lordello,M.L.L.; Agostinho,C.L.O.; Laudanna,A.A.

The pathogenesis of nonsteroidal anti-inflammatory drug (NSAID) enteropathy is a complex process involving the uncoupling of mitochondrial oxidative phosphorylation and inhibition of cyclooxygenase (COX). Rofecoxib, a selective inhibitor of COX-2, has shown less gastric damage, but the same beneficial effect is not clear in the case of the small bowel. Fifty-seven male Wistar rats (250-350 g) were divided into ...

Data: 2004   |   Origem: OASIS br

Intestinal permeability in strongyloidiasis

Werneck-Silva,A.L.; Sipahi,A.M.; Damião,A.O.M.C.; Buchpigue,C.A.; Iriya,K.; Laudanna,A.A.

The objective of the present study was to assess intestinal permeability in patients with infection caused by Strongyloides stercoralis. Twenty-six patients (16 women and 10 men), mean age 45.9, with a diagnosis of strongyloidiasis were evaluated. For comparison, 25 healthy volunteers (18 women and 7 men), mean age 44.9, without digestive disorders or intestinal parasites served as normal controls. Intestinal p...

Data: 2001   |   Origem: OASIS br

Lymphangioma of the mediastinum as a cause of chylopericardium.

de Menezes, I C; Serviço de Pediatria, Hospital de Santa Maria, Carnaxide.; Araújo e Sá, G; Damião, A; Telo, M; Martins, F M; Macedo, M M

Chylopericardium is a rare from of pericardial effusion. A case of a ten-year-old female patient with a chylopericardium incidentally detected during a mild respiratory infection through cardiac enlargement at the chest X ray is reported. The techniques used to achieve this diagnosis are described, a special emphasis being put on the CT-scan and lymphangiography, which have not been used in such cases so far. T...

Data: 1990   |   Origem: Acta Médica Portuguesa

Prevalence of extracranial carotid occlusive disease. Non-invasive study.

Fernandes, J F; Instituto Vascular de Lisboa.; Pedro, L M; Freire, J P; Correia, A; Pedro, M M; Damião, A; Pereira, R; Alves, J P; Martins, C

Cerebrovascular disease is the most important cause of mortality and morbility in some European Countries, but the prevalence of carotid occlusive disease has not been adequately assessed. From 1985 to 1987, 1,143 patients were consecutively evaluated in the Vascular Laboratory in order to determine the presence of extracranial carotid occlusive disease. 638 (55.8%) were males and 505 (44.2%) females and mean a...

Data: 1970   |   Origem: Acta Médica Portuguesa

Role of endarterectomy in the secondary prevention of cerebrovascular accidents...

Ferro, J M; Oliveira, V; Melo, T P; Crespo, M; Lopes, J; Fernandes e Fernandes, J; Damião, A; Campos, J G

Data: 1970   |   Origem: Acta Médica Portuguesa

Carotid artery surgery in extracranial occlusive disease and cerebral ischemia....

Fernandes e Fernandes, J; Serviço de Cirurgia Vascular, Hospital de Santa Maria, Faculdade de Medicina, Lisboa.; Damião, A; Freire, J P; Pedro, L M

Carotid artery surgery became an established procedure for the treatment of cerebrovascular insufficiency associated with carotid artery stenosis and for the prevention of Stroke. 180 patients were consecutively treated because of occlusive disease of the carotid arteries: 152 (84%) had TIA's or reversible deficits, 11 (6.1%) had strokes with partial recovery, 16 (8.8%) asymptomatic carotid disease and 1 patien...

Data: 1970   |   Origem: Acta Médica Portuguesa

The role of stents in endovascular surgery.

da Cunha e Sá, D; Instituto Vascular de Lisboa, Hospital Particular de Lisboa.; Damião, A; Fernandes e Fernandes, J

Stent appears as the most recent and revolutionary acquisition in Endovascular Surgery. It represents the percutaneous permanent placement of a Vascular prosthesis. We discuss its background and evolution, the several types as well as some of its characteristics as biocompatibility, trombogenicity and biomechanics. We also describe practical aspects concerning the placement procedure. It is also discussed the p...

Data: 1970   |   Origem: Acta Médica Portuguesa

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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia